Results 31 to 40 of about 2,133 (160)

Caregiver Perspectives on the Burden of Disease and Treatment in Uncontrolled Gout

Arthritis Care &Research, EarlyView.
Objective Uncontrolled gout (UG) refers to persistently elevated serum urate (SU) levels >6 mg/dL and ongoing gout symptoms despite use of urate‐lowering therapy (ULT). The objective of this study was to evaluate the burden associated with informal caregiving for individuals with UG.
Angelo Gaffo, Bhavisha Desai, Abiola Oladapo, Nana Kragh, Rebekah Zincavage, Brad Padilla, Naomi Schlesinger   +6 more
wiley   +1 more source

Pseudotumoral tophaceous involvement of the Achilles paratenon

Journal of the Belgian Society of Radiology, 2015
Gout is the most common form of microcrystalline arthropathy which usually does not pose a diagnostic challenge when patients have typical presentation, appropriate biochemical picture and classical radiographic appearance.
Thomas Ryckaert, I. Crevits, S. Brijs, G. Debakker, F. Rosseel, A. Tieleman, R. De Man   +6 more
doaj   +1 more source

Efficacy and Safety of Nanoencapsulated Sirolimus Plus Pegadricase: Results From the Randomized, Placebo‐Controlled Phase 3 Trials

Arthritis &Rheumatology, EarlyView.
Objective DISSOLVE I and II examined the efficacy and safety of nanoencapsulated sirolimus (NAS) plus pegadricase (NASP) in patients with uncontrolled gout (UG). Methods In these double‐blind, placebo‐controlled Phase 3 trials of NASP, patients were randomized 1:1:1 to infusions of high‐dose (HD) or low‐dose (LD) NAS plus pegadricase (HD NASP, LD NASP,
Herbert S. B. Baraf, Puja P. Khanna, Milan Petronijevic, Mamuka Lortkipanidze, Anand Patel, Kwabena Ayesu, Michael H. Pillinger, Atul Singhal, Joanna Sobierska, Jacquie Christie, Peter Traber, Rehan Azeem, Wesley DeHaan, Hugues Santin‐Janin, Bhavisha Desai, Alan Kivitz   +15 more
wiley   +1 more source

Gouty Panniculitis with Ulcerations in a Patient with Multiple Organ Dysfunctions

Case Reports in Rheumatology, 2014
Gouty panniculitis is a rare manifestation of gout. Clinically, it is characterized by indurated subcutaneous nodules in nonjoint areas. Pathologically, typical characteristic gouty tophi can be seen in subcutaneous tissue.
Lu Wang, Crystal Rose, Paul Mellen, George Branam, Maria M. Picken   +4 more
doaj   +1 more source

Cytological Diagnosis of Gouty Tophi in Two Cases with Different Clinical Presentation [PDF]

National Journal of Laboratory Medicine, 2015
Gout is caused by persistent chronic hyperuricemia and is characterised clinically by relapsing and remitting attacks of joint pain. The deposition of monosodium urate crystals in and around joints, skin and soft tissue produces masses commonly ...
Renu Thambi , Subitha .K, Lekshmi devi , Lillykutty Pothen   +3 more
doaj   +1 more source

Sequential catalytic nanosystem of carbon dots and uricase integrated with polydopamine for therapy of gouty wound ulceration

BMEMat, EarlyView.
Sequential dual‐catalytic treatment of the gout wound ulceration process by CDs‐Uri@PDA. (a) Synthesis steps and morphology of CDs‐Uri@PDA. (b) Sequential treatment process and mechanism of CDs‐Uri@PDA for gout wound ulceration according to (i) uric acid reduction, (ii) antibacterial activity, and (iii) anti‐inflammatory effects.
Yonglan Yang, Yang Yang, Pengpeng Ma, Ruiqi Zhu, Xia Pan, Shaoling Zheng, Bo Chen, Yanli Jin, Youcong Gong, Jie Liu, Tianwang Li, Xu Chen   +11 more
wiley   +1 more source

Ultrasound Findings in Symptomatic HADD of the Hand and Wrist. A Case Series of 37 Patients

Journal of Clinical Ultrasound, EarlyView.
Ultrasound enables accurate diagnosis of hydroxyapatite deposition disease of the hand and wrist in patients with acute, non‐traumatic pain, typically in middle‐aged women. Characteristic calcifications, often in the resorptive phase, support diagnosis, while radiography may confirm findings without the need for advanced imaging.
Marco Becciolini, Riccardo Picasso, Antonio Corvino, Federico Zaottini   +3 more
wiley   +1 more source

Obesity, Echocardiographic Changes and Framingham Risk Score in the Spectrum of Gout: A Cross-Sectional Study

The Turkish Journal of Gastroenterology, 2019
Objectives: This study aims to establish cardiovascular risk in obese and non-obese patients in stages of gout by using Framingham risk score (FRS) and transthoracic echocardiography.
Rada GANCHEVA, Atanas KOUNDURDJIEV, Mariana IVANOVA, Todor KUNDURZHIEV, Zlatimir KOLAROV   +4 more
doaj  

Correlations of characteristics with tissue involvement in knee gouty arthritis: Magnetic resonance imaging analysis

Heliyon
Objective: This study investigates the MRI features of knee gouty arthritis (KGA), examines its relationship with the extent of tissue involvement, and assesses whether risk factors can predict KGA.
Qingshuai Wang, Bo Chen, Zhicheng Zhang, Xiongfeng Tang, Yingzhi Li   +4 more
doaj   +1 more source

When Joint Aspiration Fails: Point‐of‐Care Ultrasound for Diagnosing Chronic Gout in Prolonged Monoarthritis

Journal of General and Family Medicine, Volume 27, Issue 5, September 2026.
ABSTRACT Background A 34‐year‐old man presented to our primary care clinic with persistent pain and swelling of the right first metatarsophalangeal joint lasting 3 months. A previous clinic had suspected gout based on hyperuricemia, but urate‐lowering therapy was repeatedly withheld because of ongoing inflammation, resulting in prolonged symptoms ...
Takayuki Yamada
wiley   +1 more source