Results 91 to 100 of about 4,999,446 (322)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Feasibility of the Implementation of Activity-Based Costing (ABC) in Operational Budgeting of Government Agencies (A Case Study of Government Agencies of Isfahan Province) [PDF]

open access: yesحسابداری سلامت, 2012
Introduction: This research investigated the factors affecting implementation of activity based costing (ABC) in operational budgeting of government agencies in Isfahan province.
D. Foroghi   +2 more
doaj  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Environmental scanning and analysis in Swedish central government agencies

open access: yesOffentlig Förvaltning: Scandinavian Journal of Public Administration, 2012
<p>Most government agencies have some form of environmental scanning, but few have dedicated departments or full-time staff responsible for analysis.
Torbjörn Lundqvist
doaj  

Funding Gaps and Government Shutdowns: CRS Experts [PDF]

open access: yes, 2011
[Excerpt] In the event of a funding gap, the potential impacts of a government shutdown will depend on a program’s or agency’s specific circumstances and how relevant law is interpreted.
Brass, Clinton T
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Methodological approaches to the institutional transformations for the formation and development of the scientific and industrial complex (on the example of the Republic of Belarus)

open access: yesEkonomika Nauki
Even large industrial enterprises do not have sufficient potential to implement large-scale innovation projects, which would allow, on the one hand, to ensure the high-tech products production and, on the other hand, to overcome the consequences of ...
A. G. Shumilin, I. V. Ustinovich
doaj   +1 more source

Determinants of farmers' trust in government agricultural agencies in Poland

open access: yesAgricultural Economics (AGRICECON), 2010
The purpose of this study was to investigate the levels of farmers' trust toward state agricultural agencies in Poland, to identify its determinants and to develop a model illustrating the relationship between trust and the different dimensions of the ...
Aldona ZAWOJSKA
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

The Financial and Accounting Information: a Genuine Power Factor, in the Report Win - Loss of the Investment on the Capital Market [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2016
The accounting information can be assimilated and analyzed based on three aspects: semantic,syntactic and pragmatic. The semantic aspect of the information refers to its importance for thereceiving element.
Claudia Nicoleta Guni
doaj  

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