Results 31 to 40 of about 2,006,808 (290)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Book Review: "The Economists' Hour: False Prophets, Free Markets, and the Fracture of Society"

open access: yesQuarterly Journal of Austrian Economics, 2020
Binyamin Appelbaum's new book, _The Economists' Hour_ argues that nefarious free market economists took over economic policy around 1950, and promotes democratic constraints on markets as a solution.
David Gordon
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Re-Innovation from Failure, Institutional Environmental Differences, and Firm Performance: Evidence from China [PDF]

open access: yesAmfiteatru Economic, 2020
Due to an anti-failure bias, theoretical and practical studies have not focused much on the problem of innovation failure. The literature does not include studies on how the effect of re-innovation input on firm performance can still be explained by ...
Zhuang Xiong, Pengju Wang , Yu Zhao
doaj   +1 more source

Government Failures in Development [PDF]

open access: yesJournal of Economic Perspectives, 1990
By the 1970s and early 1980s, governments in most developing countries were mired down in economic policies that were manifestly unworkable. Whether market failures had been present or not, most knowledgeable observers concluded that there had been colossal government failures.
openaire   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Readiness of local government in PPP project development - case of LRT Bandung [PDF]

open access: yesMATEC Web of Conferences, 2019
Infrastructure development with PPP (Public Private Partnership) scheme is a relatively new concept applied by the Indonesian construction industry as an alternative to overcome delays and the low absorption of the Indonesian Government Budget (APBN) and
Putri Revana, Wirahadikusumah Reini D.
doaj   +1 more source

MBS taskforce fails the pub test

open access: yesJournal of Perioperative Nursing, 2021
The nursing profession has been frustrated by a government review body that has ignored evidence-based recommendations resulting in a failure to meet community expectations.
Toni Hains   +2 more
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

On the Failure to Reach the Optimal Government Debt Ceiling

open access: yesRisks, 2018
We develop a government debt management model to study the optimal debt ceiling when the ability of the government to generate primary surpluses to reduce the debt ratio is limited. We succeed in finding a solution for the optimal debt ceiling.
Abel Cadenillas, Ricardo Huamán-Aguilar
doaj   +1 more source

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