Results 91 to 100 of about 1,619,009 (384)

Environmental regulation and governance

, 2017
This chapter provides an overview of the recent new environmental governance (NEG) trend and maps the shifts in environmental regulation and governance that led us here. It also highlights recent debates and unresolved challenges for governing the environment. In such a short chapter, much of what will be discussed will inevitably caricature the wealth
openaire   +3 more sources

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Protection against Government Takings: Compensation for Regulation? [PDF]

The paper responds to recent debate in New Zealand on the power of the government to take private property, directly or through regulatory constraints. This aspect of regulation has received less attention in New Zealand than it warrants.
Kevin Guerin
core  

Sosialisasi Peraturan Daerah Kota Pariaman Nomor 20 Tahun 2012 Tentang Jaminan Kesehatan Sabiduak- Sadayuang (JK-SS) Dalam Rangka Memberikan Jaminan Kesehatan Masyarakat Di Kecamatan Pariaman Tengah, Kota Pariaman

Warta Pengabdian Andalas, 2016
Applicable local Pariaman Number 20 in 2012 About Providence health coverage Sabiduak Sadayuang (JK-SS) was established by the Government of Pariaman as a policy area in order to improve the policies of the Central Government to enact public health ...
Delfina Gusman, Arfiani Arfiani, Henny Andriani, Alsyam Alsyam, Charles Simabura   +4 more
doaj  

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

Post-Detection SETI Protocols & METI: The Time Has Come To Regulate Them Both [PDF]

JBIS Vol. 69 No. 8 August 2016, 2017
Regulations governing METI are weak or non-existent. Post-detection SETI protocols are non-binding and too general. Vastly increased SETI capabilities, Chinese involvement in the field, and an intensified effort by METI-ists to initiate radio transmissions to the stars are among reasons cited for urgency in addressing the question of appropriate ...
arxiv  

The Evolutionary Game of Electronic Seal Usage Behaviour Supervision From the Perspective of Credit and Penalty

IEEE Access, 2018
The illegal use of electronic seals has the potential to harm both the contracting parties and the country's economy. This paper studies the phylogenetic relationship between government regulatory bodies and enterprise behaviors through the payoff matrix
Hejun Liang, Guanghui Yuan, Yunpeng Yang, Jianzheng Yang, Chongjun Fan   +4 more
doaj   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Assessing The Effectiveness Of Current Cybersecurity Regulations And Policies In The US [PDF]

This article assesses the effectiveness of current cybersecurity regulations and policies in the United States amidst the escalating frequency and sophistication of cyber threats. The focus is on the comprehensive framework established by the U.S. government, with a spotlight on the National Institute of Standards and Technology (NIST) Cybersecurity ...
arxiv   +1 more source

Studying urban climate governance: Where to begin, what to look for, and how to make a meaningful contribution to scholarship and practice

Earth System Governance, 2019
Cities are key in climate mitigation and adaptation, and they have developed into sites of innovative urban climate governance that can spur on climate action.
Jeroen van der Heijden
doaj