Results 61 to 70 of about 869,766 (268)
Dynamic Ontology Supporting Local Government [PDF]
, 2018 Nowadays in information society we face a huge amount of data and information sharing on the Web by customers of public administrator sectors. Services performed for customers from the nature are very flexible – so preparation ontology for such goals must include dynamic aspects.
Mieczyslaw L. Owoc +2 more
openaire +2 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
GOVERNMENT SUPPORT OF SINGLE-INDUSTRY TOWNS IN RUSSIA AND KAZAKHSTAN
Финансы: теория и практика, 2017 The article discusses the results of research aimed at conducting the comparative analysis of implementation of the state policy for support of single-industry towns in Russia and Kazakhstan, the identification of specific and common problems as well as ...
I. D. Turgel, L. L. Bozhko, Linshui Xu
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
TARGETED PROGRAMS AS A TOOL FOR REGIONAL DEVELOPMENT
Финансы: теория и практика, 2017 The preservation of the national cultural heritage is a strategically important task currently faced by the Russian Federation. Traditional national handicrafts which are an important part of the national heritage are now on the edge of survival.
M. V. Rapoport
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Factors Influencing Small and Medium Enterprise Performance in Nigeria: A Pilot Study
Journal of Business Management and Accounting, 2018 This paper discusses factors influencing the performance of SMEs in Nigeria using the quantitative approach. The study used a survey method; it administered 40 questionnaires to SME owner-managers randomly selected in Kano, Nigeria.
Maryam Imam Ibrahim +2 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source