Results 81 to 90 of about 869,766 (268)

Identifying strategies to support implementation of interprofessional primary care teams in Nova Scotia: Results of a survey and knowledge sharing event

BMC Primary Care
Background Interprofessional primary care teams (IPCTs) work together to enhance care. Despite evidence on the benefits of IPCTs, implementation remains challenging.
Amy Grant, Rachel Giacomantonio, Kelly Lackie, Adrian MacKenzie, Elizabeth Jeffers, Julia Kontak, Emily Gard Marshall, Susan Philpott, Debbie Sheppard-LeMoine, Elizabeth Lappin, Alice Bruce, Amy Mireault, Deanna Beck, Lindsay Cormier, Ruth Martin-Misener   +14 more
doaj   +1 more source

Evaluating Capacity-Building through Literature: A Review of Studies on the Training and Development of Cooperative Development Officers in the Philippines

JPAIR
In the Philippines, the professionalization of Cooperative Development Officers (CDOs) has been institutionalized through the implementation of Republic Act No. 11535, which was signed into law on April 9, 2021, and Memorandum Circular No.
Ralph Rendell Toledo, Emerlita De Jesus, Darriela Lane Estrada, Josue Jr. Sotoza, Clarence Garces   +4 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Covid-19, credit risk management modeling, and government support. [PDF]

J Bank Financ, 2023
Telg S, Dubinova A, Lucas A.
europepmc   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Conceptual modeling in insurance agricultural risks

Путеводитель предпринимателя, 2020
The article discusses the possibility of using the method of conceptual modeling for revision of the Concept development of the agricultural insurance, implemented with state support, for the period up to 2020.
V. V. Shcherbakov
doaj  

Assessment of the impact of management commitment and supply chain integration on SMEs' innovation performance: Moderation role of government support. [PDF]

Heliyon, 2023
Chen H, Amoako T, Quansah CE, Danso SA, Jidda DJ.   +4 more
europepmc   +1 more source