Results 81 to 90 of about 24,865,421 (393)

Big Data as Governmentality

open access: yes, 2014
This paper conceptualizes how large-scale data and algorithms condition and reshape knowledge production when addressing international development challenges. The concept of governmentality and four dimensions of an analytics of government are proposed as a theoretical framework to examine how big data is constituted as an aspiration to improve the ...
Flyverbom, Mikkel   +2 more
openaire   +1 more source

Childbirth in Palestine [PDF]

open access: yes, 2005
Objective: This study describes staffing, caseloads and reported routine practices for normal childbirth in Palestinian West Bank (WB) governmental maternity facilities and compares these practices with evidence-based care.
Wick, Laura
core   +1 more source

Data gathering, surveillance and human rights: recasting the debate

open access: yes, 2016
The nature and depth of internet surveillance has been revealed to be very different from what had previously been publically acknowledged or politically debated.
P. Bernal
semanticscholar   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

open access: yesFEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar   +3 more
wiley   +1 more source

Challenges and Opportunities of Non-governmental Organizations

open access: yesBulletin of the Transilvania University of Braşov: Series VII: Social Sciences, Law
Non-governmental organizations play an extremely important role in society, intervening subsidiarily for the welfare of society.This paper describes the results of an exploratory qualitative research, the ...
Diana C. Bodi
doaj   +1 more source

Validation of the Structural Model of Open Data Governance in Line with the Health of the Administrative System in E-government [PDF]

open access: yesInternational Journal of Digital Content Management
Purpose: The current research was conducted with the aim of validating the structural model of open data governance in line with the health of the administrative system in e-government in government organizations.
Ahmad Sami   +2 more
doaj   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

open access: yesFEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart   +4 more
wiley   +1 more source

A Multi-Agent Deep Reinforcement Learning System for Governmental Interoperability

open access: yesApplied Sciences
This study explores the integration of the JADE (Java Agent Development Framework) platform with deep reinforcement learning (DRL) to enhance governmental interoperability and optimize administrative workflows in municipal settings. The proposed approach
Azanu Mirolgn Mequanenit   +4 more
doaj   +1 more source

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