Results 41 to 50 of about 29,049 (260)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The image of a political entity in the regional dimension: The specifics of formation and peculiarities of perception by public opinion

open access: yesRUDN Journal of Public Administration
The research identifies key problems in the field of correcting and maintaining the image of a political subject in the mass media and deepens the differentiation of concepts from the sphere of political image.
Alexander V. Tolochko, Sergey S. Fomenko
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Instrukce pro hornolužické zeměpanské úředníky v 16. století | Instructions for Upper Lusatian officials in the 16th century [PDF]

open access: yesHistorie - Otázky - Problémy, 2019
The author focuses on the creation of the monarchical administration in Upper Lusatia as one of the Lands of the Bohemian Crown, after the mid-16th century, when significant changes in this area were made.
Tomáš Velička
doaj  

Interregional Cooperation in SCO format: Outcomes and Potential for the Novosibirsk Region

open access: yesМеждународная аналитика, 2015
The paper deals with regional cooperation of Novosibirsk region and city of Novosibirsk with SCO countries. The rich scientific, technical and educational potential as well as its geographical position can be considered as optimal place for all sorts of ...
S. Sannikov
doaj   +1 more source

KEPASTIAN HUKUM TERHADAP PEMBERHENTIAN SEMENTARA GUBERNUR DKI JAKARTA 2017

open access: yesCepalo, 2020
Basuki Tjahaja Purnama mantan gubernur DKI Jakarta saat ini sudah menjalani Putusan Pengadilan oleh Pengadilan Negri Jakarta Utara, akan tetapi sebelum putusan ini dijatuhkan terdapat sebuah permasalahan hukum mengenai kepastian hukum dalam pemberhentian
Muhammad Rizqi Fadhlillah   +1 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

The technical roadmap of the development of variable pitch propeller governors for turboprop

open access: yesHangkong gongcheng jinzhan
The variable pitch governor controls the propeller to maintain a constant speed,so that the propeller can be energy-saving and efficient in a wider range of flight envelope.
CHEN Tingting, GUO Yong, PAN Zhongjian
doaj   +1 more source

The surnames and the names of the parts of the characters in the novel of L.N. Tolstoy's «Anna Karenina»

open access: yesРазвитие образования, 2018
The article proposes an original version of the origin of the names of the main characters of the novel L.N. Tolstoy's Anna Karenina. The author of the article, exploring the novel and extensive materials on it, shows an amusing but systematic ...
Fyodor P. Khodeev
doaj   +1 more source

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