Results 61 to 70 of about 855,405 (260)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Fortunas e infortúnios ultramarinos: alguns casos de enriquecimento e conflitos políticos de governadores na América portuguesa Overseas richness and misfortunes: enrichment and politicians' conflicts of the Portuguese America's governors

open access: yesVaria História, 2012
Este artigo aborda o envolvimento de governadores da América portuguesa que vivenciaram conflitos de autoridade nas capitanias que governaram e de como estavam inseridos em redes clientelares ao longo dessas desavenças.
Marcos Aurélio de Paula Pereira
doaj   +1 more source

McDonnell v. United States: Defining “Official Action” in Public Corruption Law [PDF]

open access: yes, 2017
McDonnell v. United States involved the former Governor of Virginia leveraging the power of his position to help a wealthy constituent gain access to top state decision makers in exchange for valuable gifts and loans.
Murphy, Christopher
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Hassan Continues to Be Popular; Potential 2016 Gubernatorial Candidates Unknown 5/26/15 [PDF]

open access: yes, 2015
Governor Maggie Hassan’s favorability and job approval continues to be high among New Hampshire residents. Four potential 2016 candidates for governor are largely unknown by Granite Staters.
Survey Center, UNH
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

The image of a political entity in the regional dimension: The specifics of formation and peculiarities of perception by public opinion

open access: yesRUDN Journal of Public Administration
The research identifies key problems in the field of correcting and maintaining the image of a political subject in the mass media and deepens the differentiation of concepts from the sphere of political image.
Alexander V. Tolochko, Sergey S. Fomenko
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

A Letter from the Council of the Colony of Massachusetts Bay to the Council of Connecticut [PDF]

open access: yes, 1921
Written April 7, 1676, by Edward Rawson, the Secretary. Issued at the General Court of the Society of Colonial Wars in the State of Rhode Island and Providence Plantations by its Governor, Frederick Dickman Carr, Esq.
Rawson, Edward
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

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