Results 201 to 210 of about 24,285 (259)

mGem: Opening Env and harnessing NK cell effector functions to eliminate HIV-1-infected cells. [PDF]

mBio
Richard J, Finzi A.
europepmc   +1 more source

Framework-mediated binding of foreign and self-glycans by IGHV4-34 antibodies. [PDF]

Front Immunol
Langley DB, Jara CJ, Henry JY, Reed JH, Goodnow CC, Christ D.   +5 more
europepmc   +1 more source

The bacteriophage T4 homologous recombination system: mechanism, applications, conservation, and environmental significance. [PDF]

EcoSal Plus
Morrical SW.
europepmc   +1 more source

Design of a highly potent bifunctional HIV-1 entry inhibitor targeting both gp120 and gp41. [PDF]

RSC Med Chem
Du X, Li Q, Du S, Wang H, Shi A, Yuan M, Yu F, Liu Y, Wang C.   +8 more
europepmc   +1 more source

M-Sec promotes the production of infectious HIV-1 virus through the exocyst complex in macrophages. [PDF]

PLoS Pathog
Mahmoud RM, Hiyoshi M, Abdelnaser RA, Monde K, Monde N, Koma T, Mizuno H, Habash SA, Takahashi N, Maeda Y, Ono A, Suzu S.   +11 more
europepmc   +1 more source

Development of HIV-1 Fusion Inhibitors Targeting gp41

Current Medicinal Chemistry, 2014
The HIV-1 envelope protein glycoprotein 41 (gp41) is crucial in the HIV-1 infection process, therefore gp41 has emerged as an attractive target for drug design against AIDS. During the past few decades, tremendous efforts have been made on developing inhibitors that can prevent the HIV-1 entry process via suppressing functional gp41.
Fangwei Shao
exaly   +6 more sources

HIV‐1 gp41 and gp160 are hyperthermostable proteins in a mesophilic environment

European Journal of Biochemistry, 2004
HIV gp41(24–157) unfolds cooperatively over the pH range of 1.0–4.0 with Tm values of > 100 °C. At pH 2.8, protein unfolding was 80% reversible and the ΔHvH/ΔHcal ratio of 3.7 is indicative of gp41 being trimeric. No evidence for a monomer–trimer equilibrium in the concentration range of 0.3–36 µm was obtained by DSC and tryptophan fluorescence ...
Krell, Tino, Greco, Frédéric, Engel, Olivier, Dubayle, Jean, Dubayle, Joseline, Kennel, Audrey, Charloteaux, Benoît, Brasseur, Robert, Chevalier, Michel, Sodoyer, Régis, El Habib, Raphaëlle   +10 more
openaire   +4 more sources