Results 161 to 170 of about 81,481 (258)

Author Correction: Simultaneous activation of CXC chemokine receptor 4 and histamine receptor H1 enhances calcium signaling and cancer cell migration

Scientific Reports
Chulo Park, Jin‑Woo Lee, Kiheon Kim, Dong‑Seung Seen, Jae‑Yeon Jeong, Won‑Ki Huh   +5 more
doaj   +1 more source

Arrestins as programmable integrators of GPCR signaling: structural microstates, spatiotemporal logic, and therapeutic control. [PDF]

Cell Discov
He Q, Zhao LH, Xu HE.
europepmc   +1 more source

Taste‐Active Peptides: Sensation Mechanisms and Structure–Taste Relationships

Sensory Neuroscience, EarlyView.
Overview of taste‐active peptides, including taste bud cellular organization, peptide–receptor interactions and signaling pathways, structure–taste relationships, and integrated computational and experimental strategies for peptide discovery, mechanism elucidation, and flavor modulation.
Dengyi Pei, Jucai Xu, Weizu Yu, Quanyou Guo, Wenmeng He   +4 more
wiley   +1 more source

DeorphaNN: Virtual screening of GPCR peptide agonists using AlphaFold-predicted active-state complexes and deep learning embeddings. [PDF]

Mol Cell
Ferguson L, Ouellet S, Vandewyer E, Wang C, Wunna Z, Lim TKY, Schafer WR, Beets I.   +7 more
europepmc   +1 more source

Molecular glues: Recent advances in cereblon substrate identification and mechanistic insights

Smart Molecules, EarlyView.
Molecular glues exert diverse core biological functions by inducing or stabilizing protein–protein interactions, extending far beyond the traditional scope of targeted protein degradation. Key breakthroughs include expanded cereblon substrate recognition, sustained G protein‐coupled receptor megacomplex signaling, and the first orthosteric molecular ...
Qingyun Guan, Xiaoyu Shi, Qian Yang, Xiangyi Jiang, Xinyong Liu, Peng Zhan   +5 more
wiley   +1 more source

Transcriptional Reprogramming of GPCR Signaling Pathways in the Frontal Cortex of Morphine Dependent Mice. [PDF]

Biomol Ther (Seoul)
Kim M, Moon S, Yayeh T, Villa T, Oh S.
europepmc   +1 more source

Calcitonin‐like diuretic hormone influences reproduction in adult female Rhodnius prolixus

Insect Science, EarlyView.
Highlights • CT/DH‐like immunoreactivity is present in female reproductive tissues • CT/DH receptor transcripts are expressed in the fat body and ovaries • RNAi knockdown of CT/DH receptors reduces egg number and hatching rate • Rhopr‐CT/DH increases RhoprVg1 and RhoprVgR expression in ovaries in vitro • Rhopr‐CT/DH stimulates oviduct contractions in a
Areej N. Al‐Dailami, Ian Orchard, Angela B. Lange   +2 more
wiley   +1 more source

A Sesquiterpenoid from <i>Schizophyllum commune</i> Protects C17.2 Neural Stem Cells Against Oxidative Stress Through Modulation of GPCR-Associated Signaling Pathways. [PDF]

Int J Mol Sci
Li L, Zou G, Wang Q, Jiang H, Wu X, Zhao J, Zhang H, Wang X, Li S.   +8 more
europepmc   +1 more source

Prostaglandin E2 (PGE2) signaling regulates fluid excretion and uric acid metabolism in the mosquito Anopheles gambiae

Insect Science, EarlyView.
Prostaglandin E2 (PGE2) signaling via its receptor has integral roles in mosquito physiology, mediating fluid excretion, stimulating hindgut contractions, and in modulating uric acid levels. Together, these results uncover previously unrecognized roles of prostaglandin signaling in osmotic balance and metabolic homeostasis in mosquitoes.
Hyeogsun Kwon, David R. Hall, Houda O. Maaroufi, Ryan C. Smith   +3 more
wiley   +1 more source

Advances in Cyclic Peptides Targeting G Protein-Coupled Receptors. [PDF]

Chembiochem
Zhou Y, Li N, Zheng JS.
europepmc   +1 more source