Results 61 to 70 of about 141,350 (263)

Amyloidogenic Peptide Fragments Designed From Bacterial Collagen‐like Proteins Form Hydrogel

Advanced Functional Materials, EarlyView.
This study identified amyloidogenic sequence motifs in bacterial collagen‐like proteins and exploited these to design peptides that self‐assemble into β‐sheet fibers and form hydrogels. One hydrogel supported healthy fibroblast growth, showing promise for biocompatible materials. Our work demonstrates that bacterial sequences can be harnessed to create
Vamika Sagar, Xuen J Ng, Lukas Lechel, Ashish Chand Rajwar, Hendrik Bargel, Abhishek A. Jalan   +5 more
wiley   +1 more source

Isospectrality of conventional and new extended potentials, second-order supersymmetry and role of PT symmetry

, 2009
We develop a systematic approach to construct novel completely solvable rational potentials. Second-order supersymmetric quantum mechanics dictates the latter to be isospectral to some well-studied quantum systems.
A. A. Andrianov, A. A. Andrianov, A. A. Andrianov, A. Contreras-Astorga, A. Mitra, A. Mostafazadeh, A. Sinha, B. Bagchi, B. Bagchi, B. Bagchi, B. Bagchi, B. Bagchi, B. Bagchi, B. F. Samsonov, B. Mielnik, B. Mielnik, B. Roy, C. M. Bender, C. Quesne, C. Quesne, C. V. Sukumar, D. Gómez-Ullate, D. Gómez-Ullate, D. J. Fernández, F. Cooper, G. Junker, G. Junker, G. Lévai, G. Lévai, L. E. Gendenshtein, M. Abramowitz, R. Roychoudhury, V. Bargmann, Z. Ahmed, Z. Ahmed   +34 more
core   +1 more source

CORE: Cholesterol Altered Lipid Nanoparticles for Splenic Expression of mRNA Payloads

Advanced Healthcare Materials, EarlyView.
In this paper researchers introduce CORE LNPs, a new class of lipid nanoparticles engineered to redirect mRNA expression away from the liver and into the spleen, a key immune organ. By combining chemical design with computational tools, they created cholesterol analogs that enable precise spleen‐targeted expression, providing greater applications for ...
Eshan A. Narasipura, Vincent Fung, Rachel VanKeulen‐Miller, Palas B. Tiwade, Owen S. Fenton   +4 more
wiley   +1 more source

Generative artificial intelligence in graduate medical education

Frontiers in Medicine
Generative artificial intelligence (GenAI) is rapidly transforming various sectors, including healthcare and education. This paper explores the potential opportunities and risks of GenAI in graduate medical education (GME).
Ravi Janumpally, Suparna Nanua, Andy Ngo, Kenneth Youens   +3 more
doaj   +1 more source

Key Features of GPT Learning Paradigm [PDF]

Annals of Dunarea de Jos University. Fascicle I : Economics and Applied Informatics
The continuous advancement of technology has always sparked debates, much like earlier shifts in history. From the introduction of computers in the mid-20th century to the rise of the internet in the 2000s, each innovation has brought both excitement and
Madalina Pana
doaj   +1 more source

Comparative performance of humans versus GPT-4.0 and GPT-3.5 in the self-assessment program of American Academy of Ophthalmology

Scientific Reports, 2023
To compare the performance of humans, GPT-4.0 and GPT-3.5 in answering multiple-choice questions from the American Academy of Ophthalmology (AAO) Basic and Clinical Science Course (BCSC) self-assessment program, available at https://www.aao.org/education/
Andrea Taloni, Massimiliano Borselli, Valentina Scarsi, Costanza Rossi, Giulia Coco, Vincenzo Scorcia, Giuseppe Giannaccare   +6 more
doaj   +1 more source

Text Mining of CVD Synthesis Recipes for 2D Materials

Advanced Materials, EarlyView.
A lightweight, multi‐stage natural language processing framework utilizes fine‐tuned BERT models to extract chemical vapor deposition synthesis knowledge from diverse 2D materials literature. The domain‐adapted workflow integrates classification, named entity recognition, and extractive question answering to systematically retrieve categorical and ...
Ang‐Yu Lu, Richard A. Chen, Aijia Yao, Meng‐Chi Chen, Ji‐Hoon Park, Tianyi Zhang, Xudong Zheng, Nannan Mao, Jiangtao Wang, Zhien Wang, Tomás Palacios, Jing Kong   +11 more
wiley   +1 more source

Efficacy and Safety Assessment of 5‐Fluorouracil, Irinotecan and Oxaliplatin‐Loaded Implants in Mouse and Pig Models for Pancreatic Cancer Therapy

Advanced Materials, EarlyView.
A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade, Ashna A. Kumar, Samuel O. Nitschke, Paul Joyce, Elahe Minaei, Stephanie E. Reuter Lange, Chelsea Penney, Holly Warren, Ruby Shepherd, Jeremy N. Dinoro, Gordon G. Wallace, Anthony Dosseto, Sameera Ansar, Naila Islam, Alistair Lochhead, George Sharbeen, Phoebe A. Phillips, Morteza Aghmesheh, Wayne J. Hawthorne, Kara L. Vine‐Perrow   +19 more
wiley   +1 more source

Artificial Intelligence Plant Doctor: Plant Disease Diagnosis Using GPT4-vision [PDF]

Research in Plant Disease
Integrated pest management is essential for controlling plant diseases that reduce crop yields. Rapid diagnosis is crucial for effective management in the event of an outbreak to identify the cause and minimize damage.
Yoeguang Hue, Jea Hyeoung Kim, Gang Lee, Byungheon Choi, Hyun Sim, Jongbum Jeon, Mun-Il Ahn, Yong Kyu Han, Ki-Tae Kim   +8 more
doaj   +1 more source

Scalable Task Planning via Large Language Models and Structured World Representations

Advanced Robotics Research, EarlyView.
This work efficiently combines graph‐based world representations with the commonsense knowledge in Large Language Models to enhance planning techniques for the large‐scale environments that modern robots will need to face. Planning methods often struggle with computational intractability when solving task‐level problems in large‐scale environments ...
Rodrigo Pérez‐Dattari, Zhaoting Li, Robert Babuška, Jens Kober, Cosimo Della Santina   +4 more
wiley   +1 more source