Results 141 to 150 of about 7,185 (234)

CEACAM1 negatively regulates platelet-collagen interactions and thrombus growth in vitro and in vivo [PDF]

, 2009
Carcinoembryonic antigen cell adhesion molecule-1 (CEACAM1) is a surface glycoprotein expressed on various blood cells, epithelial cells, and vascular cells.
Beauchemin, N, Chand, R, Jackson, D, Liu, Y, Ni, H, Nieswandt, B, Oates, L, Reheman, A, Wee, J, Wong, C, Yip, C   +10 more
core  

Differential regulation of actin stress fiber assembly and proplatelet formation by α2β1 integrin and GPVI in human megakaryocytes [PDF]

, 2004
Siham Sabri, Martine Jandrot‐Perrus, Jacques Bertoglio, Richard W. Farndale, Véronique Mansat‐De Mas, Najet Debili, William Vainchenker   +6 more
openalex   +1 more source

Defective collagen-induced platelet activation in two patients with malignant haemopathies is related to a defect in the GPVI-coupled signalling pathway [PDF]

, 2004
Marie Geneviève Huisse, Bernadette Boval, Patricia Hainaud, Annie Robert, Françoise Fauvel-Lafève, Martine Jandrot‐Perrus, Sylvia Bellucci   +6 more
openalex   +1 more source

GPVI and α2β1 play independent critical roles during platelet adhesion and aggregate formation to collagen under flow [PDF]

, 2005
Kendra L. Sarratt, Hong Chen, Mary M. Zutter, Samuel A. Santoro, Daniel A. Hammer, Mark L. Kahn   +5 more
openalex   +1 more source

Multisite phosphorylation in platelets stimulated via glycoprotein VI and G protein-coupled receptors:interactions and functional impact [PDF]

By employing a comprehensive exploration of the molecular mechanisms of human platelet activation, this thesis investigates the mechanism of platelet activation and their function, thereby contributing to advancements in platelet biology and pharmacology.
Zhang, Pengyu
core   +1 more source

Ultra-high-throughput Ca2+ assay in platelets to distinguish ITAM-linked and G-protein-coupled receptor activation

iScience, 2022
Summary: Antiplatelet drugs targeting G-protein-coupled receptors (GPCRs), used for the secondary prevention of arterial thrombosis, coincide with an increased bleeding risk. Targeting ITAM-linked receptors, such as the collagen receptor glycoprotein VI (
Delia I. Fernández, Isabella Provenzale, Hilaire Y.F. Cheung, Jan van Groningen, Bibian M.E. Tullemans, Alicia Veninga, Joanne L. Dunster, Saman Honarnejad, Helma van den Hurk, Marijke J.E. Kuijpers, Johan W.M. Heemskerk   +10 more
doaj  

Laminin stimulates spreading of platelets through integrin α6β1–dependent activation of GPVI [PDF]

, 2005
Osamu Inoue, Katsue Suzuki‐Inoue, Owen J. T. McCarty, Masaaki Moroi, Zaverio M. Ruggeri, Thomas J. Kunicki, Yukio Ozaki, Steve P. Watson   +7 more
openalex   +1 more source

A global proteomics approach identifies novel phosphorylated signaling proteins in GPVI‐activated platelets: Involvement of G6f, a novel platelet Grb2‐binding membrane adapter [PDF]

, 2006
Ángel Galindo García, Yotis A. Senis, Robin Antrobus, Craig E. Hughes, Raymond A. Dwek, Steve P. Watson, Nicole Zitzmann   +6 more
openalex   +1 more source

Characterization of a patient with glycoprotein (GP) VI deficiency possessing neither anti‐GPVI autoantibody nor genetic aberration [PDF]

, 2006
H. Kojima, Masaaki Moroi, Stéphanie Jung, Shinya Goto, Noriko Tamura, Yukinori Kozuma, Kazumi Suzukawa, Toshiro Nagasawa   +7 more
openalex   +1 more source

A major role for Scar/WAVE‐1 downstream of GPVI in platelets [PDF]

, 2007
Simon D. J. Calaminus, Owen J. T. McCarty, Jocelyn M. Auger, Andrew C. Pearce, Robert H. Insall, Steve P. Watson, Laura M. Machesky   +6 more
openalex   +1 more source