Results 261 to 270 of about 61,907 (295)

Localization and characterization of glutathione peroxidase (GPx) in boar accessory sex glands, seminal plasma, and spermatozoa and activity of GPx in boar semen

Theriogenology, 2008
Boar ejaculate owes its characteristic large volume mainly to accessory sex gland (ASG) secretions. These are main contributors to the protective functions of seminal plasma, especially against oxidative damage. Numerous antioxidants have been detected in ASG secretions, and, respectively, in seminal plasma.
L, Jelezarsky, Ch, Vaisberg, T, Chaushev, E, Sapundjiev   +3 more
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Evolutionary and Structural Insights Into the Multifaceted Glutathione Peroxidase (Gpx) Superfamily

Antioxidants & Redox Signaling, 2008
Glutathione peroxidase (GPx) is a widespread protein superfamily found in many organisms throughout all kingdoms of life. Although it was initially thought to use only glutathione as reductant, recent evidence suggests that the majority of GPxs have specificity for thioredoxin.
TOPPO, STEFANO, VANIN, STEFANO, BOSELLO TRAVAIN, VALENTINA, TOSATTO, SILVIO   +3 more
openaire   +3 more sources

Thiols Oxidation for the Evaluation of Gpx-Like Activity

Phosphorus, Sulfur, and Silicon and the Related Elements, 2013
The glutathione peroxidase (Gpx) is one of the most important enzymes involved in protection from oxidative stress in humans.
SANTI, Claudio, GALLI, Francesco, PIRODDI, MARTA, TIDEI, CATERINA   +3 more
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A Photo‐responsive Catalytic Vesicle with GPx Activity

Chinese Journal of Chemistry, 2013
AbstractGlutathione peroxidase (GPx) is a vital antioxidant enzyme involved in the reduction of reactive oxygen species and protects cells from oxidative damage. Consequently enormous efforts have been devoted to developing artificial catalysts with GPx function.
Ruiqing Xiao, Lipeng Zhou, Zeyuan Dong, Yuzhou Gao, Junqiu Liu   +4 more
openaire   +1 more source

Discussion on the Influence of Gpx 4 Target in the Field of Cancer

Current Medicinal Chemistry
The current review was undertaken to collate data on Gpx4 inhibitors and the regulatory proteins related to Gpx4. Gpx4 plays an essential role in ferroptosis; it can be used to determine the Gpx4 as an indicator for determining tumor occurrence and as a means of treating cancer.
Ya-Lan, Wang, Hong-Yan, Guo, Tong, Zhou, Ke, Sun, Qing-Kun, Shen, Xiao-Ting, Li   +5 more
openaire   +2 more sources

Allelic Loss at the GPx-1 Locus in Cancer of the Head and Neck

Biological Trace Element Research, 2004
Glutathione peroxidase is a selenium-containing, antioxidant enzyme previously implicated in the risk and development of lung and breast cancer, in part the result of allelic loss at the GPx-1 locus. This study examined allelic loss at the same locus in squamous cell carcinomas of the head and neck.
Ya Jun, Hu, M Eileen, Dolan, Richard, Bae, Herman, Yee, Martin, Roy, Robert, Glickman, Lidia, Kiremidjian-Schumacher, Alan M, Diamond   +7 more
openaire   +2 more sources

Synthesis of telluroamino acid derivatives with remarkable GPx like activity

Org. Biomol. Chem., 2009
A series of modular telluroamino acid derivatives with remarkable GPx-like behavior was prepared in an efficient and short two-step synthesis.
Antonio L, Braga, Eduardo E, Alberto, Letiére C, Soares, João B T, Rocha, Jéssie H, Sudati, Daniel H, Roos   +5 more
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Gpx 4 is involved in the proliferation, migration and apoptosis of glioma cells

Pathology - Research and Practice, 2017
Glioma is one of the most common and aggressive types of human brain tumor, it is important to explore novel glioma-associated genes. In this report, we defined Gpx4 as a therapeutic target for glioma. Western blot and immunohistochemistry(IHC) analysis revealed that the protein level of Gpx4 was higher in glioma tissues and cell lines.
Hongyu, Zhao, Bin, Ji, Jianguo, Chen, Qingfeng, Huang, Xueguan, Lu   +4 more
openaire   +2 more sources

Genetic variations of gpx-4 and male infertility in humans.

Biology of reproduction, 2003
Phospholipid hydroperoxide glutathione peroxidase (PHGPx), the product of gpx-4, is the major selenoprotein in sperm and is considered essential for fertilization because of its multiple roles in spermatogenesis, such as hydroperoxide detoxification, formation of the mitochondrial capsule, and chromatin condensation.
MAIORINO, MATILDE, BOSELLO TRAVAIN, VALENTINA, URSINI, FULVIO, FORESTA, CARLO, GAROLLA, ANDREA, M. SCAPIN, H. SZTAJER, L. FLOHE   +7 more
openaire   +2 more sources

Heat exchanger analysis on a MicroVAX II/GPX

International Journal for Numerical Methods in Fluids, 1988
AbstractThe finite element code FIDAP was used to examine the fluid flow path within a flat plate tube/fin heat exchanger and the resulting heat transfer from the fins and tube walls. The mathematical formulation, mesh development and analysis procedure are presented, and the results obtained are compared with experimental observations of the fluid ...
openaire   +1 more source