Results 311 to 320 of about 40,571 (376)

circRNA-SORE/UBQLN1/GPX4 Mediates the Acquisition of Sorafenib Resistance in Hepatocellular Carcinoma Through Inhibition of Ferroptosis. [PDF]

MedComm (2020)
Ji L, Ruan Y, Tong M, Chen T, Cai J, Ye Z, Cai X, Xu J.   +7 more
europepmc   +1 more source

Downregulation of P2y14 Receptor Expression Ameliorates Diabetic Cardiac Autonomic Neuropathy by Inhibiting Glial Ferroptosis Via the Nrf2/Gpx4 Axis

Hongmin Guo, Taotao Peng, Yanning Gong, Congfa Zhou, Zihui Hu, Qixing Hu, Yusen Sun, Xiaoqian Ma, Zhiying Zhou, Yuanyuan Zhang, Shangdong Liang, Guilin Li   +11 more
openalex   +1 more source

Harnessing blue light photobiomodulation for cancer therapy: Evidence from a systematic review

Photochemistry and Photobiology, EarlyView.
Conventional treatments for various types of cancer are often associated with tumor recurrence and aggressiveness. Photobiomodulation with blue light (BL; 450–470 nm) emerges as a promising alternative with antitumor effects. This systematic review, with 37 in vitro and in vivo studies from 2002 to 2024, revealed that BL reduces cell viability ...
Bárbara Evelyn Santos de Lima, Rebeca Barros Nascimento, Ana Paula Mariano Santos Ginez, Maria Stella Moreira, Rebeca Boltes Cecatto, Rodrigo Labat Marcos, Maria Fernanda Setúbal Destro Rodrigues   +6 more
wiley   +1 more source

FSP1 and histone deacetylases suppress cancer persister cell ferroptosis. [PDF]

Sci Adv
Higuchi M, Williams AF, Stuhlfire AE, Nguyen AH, Gervasio DAG, Turkal CE, Chon S, Hangauer MJ.   +7 more
europepmc   +1 more source

Human spindle-shaped urine-derived stem cell exosomes alleviate severe fatty liver ischemia–reperfusion injury by inhibiting ferroptosis via GPX4

Shangheng Shi, Cunle Zhu, Shuzhen Shi, Xinqiang Li, Muhammad Imran, Qingguo Xu, Xinwei Li, Ziyin Zhao, Huan Liu, Gui Fu, Meiying Song, Xijian Huang, Feng Wang, Jinzhen Cai   +13 more
openalex   +1 more source

Lifestyle implications of the paradox and management of oxidative stress in sperm

The Journal of Physiology, EarlyView.
Abstract figure legend Lifestyle factors influencing male fertility. Schematic overview of lifestyle factors with beneficial (left) and detrimental (right) effects on male fertility. A balanced diet, regular moderate physical activity and stress management strategies support sperm function and redox homeostasis.
Giuseppe T. Patané, Ruben J. Moreira, Annamaria Russo, Maria L. Pereira, Pedro F. Oliveira, Davide Barreca, Marco G. Alves   +6 more
wiley   +1 more source

CVB3-induced P62 cleavage promotes ferroptosis through the NRF2/GPX4 axis and facilitates viral replication. [PDF]

Front Microbiol
He F, Liu Z, Feng M, Cao D, Li S, Liu X, Jiang Y, Yi X, Liu Z, Yao H.   +9 more
europepmc   +1 more source

AlphaFold3-predicted model of full-length human Phospholipid hydroperoxide glutathione peroxidase GPX4 (UniProt P36969) with Selenocysteine residue mutated to Cysteine.

Luo, Shiqi; Liu, Xinnan; Wang, Xia; liu, Haotian; Ge, Wei
openalex   +1 more source

Wogonoside Modulates the Nrf2/SLC40A1 Signaling Axis to Combat Inflammatory Osteolysis

Food Frontiers, Volume 7, Issue 2, March 2026.
This study explores the potential of wogonoside, a flavonoid from Scutellaria baicalensis, for treating inflammatory osteolysis and provides compelling experimental evidence supporting its promise as a functional food ingredient to alleviate associated bone loss.
Siyuan Zhou, Haoyu Lian, Yuangang Su, Li Wang, Jiake Xu, Jinmin Zhao, Qian Liu   +6 more
wiley   +1 more source

Characterization of Differential GPX4 Essentiality Between Intrahepatic and Extrahepatic Cholangiocarcinoma via Leveraging of a Large-Scale Functional Genomic Screen. [PDF]

Int J Mol Sci
Lee YR, Seo C, Abdullah M, Baek SH, Lee SJ.   +4 more
europepmc   +1 more source