Results 171 to 180 of about 828 (253)

A deployed investigative AI search engine for combating human trafficking at web scale

open access: yesAI Magazine, Volume 47, Issue 3, Fall 2026.
Abstract Online human trafficking investigations generate vast amounts of noisy, heterogeneous, and deliberately obfuscated data, making traditional search and analytics tools ineffective for supporting law enforcement. This paper discusses the deployment of the Domain‐Specific Insight Graphs (DIG) system, an AI‐powered investigative search engine that
Mayank Kejriwal
wiley   +1 more source

GEMA: Graph Embeddings for Multi‐Agent Coordination

open access: yesAI Magazine, Volume 47, Issue 3, Fall 2026.
Abstract Many cooperative multi‐agent tasks are naturally defined by graph‐structured objectives, where agents must collectively reach, for example, a desired relational configuration or satisfy a set of constraints. These objectives often encode spatial arrangements, inter‐agent relations, or constraints that can be formalized as target graphs ...
Alessandro Amato   +3 more
wiley   +1 more source

NAD+ Metabolism Licenses Zygotic Genome Activation via PARP7‐Mediated ADP‐Ribosylation of UHRF1 in Mouse Early Embryos

open access: yesAdvanced Science, Volume 13, Issue 51, 14 September 2026.
This study uncovers a metabolic‐epigenetic axis licensing zygotic genome activation (ZGA) in mouse embryos. A developmental decline in NAD+ levels activates PARP7, which mono‐ADP‐ribosylates and stabilizes UHRF1. This modification promotes the establishment of permissive histone acetylation marks, thereby facilitating timely ZGA.
Guangyi Cao   +13 more
wiley   +1 more source

Sacrificial Methionine Residues Protect Active‐Site Histidines From Oxidation

open access: yesAngewandte Chemie Novit, Volume 2, Issue 3, September 2026.
Methionine residues near the active site of human ribonuclease 1 act as sacrificial antioxidants, protecting catalytic histidines from oxidation by reactive oxygen species (ROS). Chemoselective capping with an oxaziridine and total chemical synthesis with a sulfur‐free norleucine isostere each render the enzyme more susceptible to oxidative ...
Evans C. Wralstad   +6 more
wiley   +1 more source

From Surface Steps to Rational Strategies: A Critical Review of Catalyst Design for Carbon Dioxide Dry Reforming of Methane

open access: yesChemCatChem, Volume 18, Issue 17, 14 September 2026.
A comprehensive overview of dry reforming of methane (DRM), linking reaction mechanisms with catalyst deactivation and rational catalyst design. Strategies based on active‐site engineering, support engineering, and operando mechanistic understanding provide a roadmap for developing durable, cost‐effective catalysts for industrial DRM.
Zihao Teng, Lizhuo Wang, Jun Huang
wiley   +1 more source

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