Results 61 to 70 of about 102,906 (305)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Urbana rasprava ususret Zagrebu XXI. stoljeća
Grad se u članku promatra kao moždano tkivo prostora i njegove se odlike suprotstavljaju kritikama urbanih koncentracija. Grad ostaje kolijevka budućnosti civilizacije.
Velimir Neidhardt
doaj
Concepções e práticas do trabalho e gestão de equipes multidisciplinares em saúde
Este trabalho trata do seguinte objetivo: conhecer as concepções e a prática de trabalho em equipe multidisciplinar sob a ótica dos gestores e dos membros das equipes.
Lucimara Alves Silva +1 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Utjecaj procesa globalizacije na planiranje prostora
Zahvaljujući utjecaju globalizacije i restrukturiranju gradova i regija, pitanja oko urbanoga i regionalnoga razvoja postala su dio stručne, ali i političke rasprave.
Sanja Šaban
doaj
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Parkovna arhitektura kao element slike grada
Sustav prometnica i ulica, struktura i tipologija izgradnje te parkovno oblikovanje tri su bitna elementa u stvaranju prepoznatljivosti i slike grada. U članku se upozorava na značenje parkovne arhitekture u oblikovanju urbanog identiteta.
Mladen Obad Šćitaroci +1 more
doaj
A coupled resonator optical waveguide (CROW) based on a slotted 1-D photonic crystal (1-D PC) cavity is proposed, and its enhancement of the optical nonlinearity due to the slow-light effect of the CROW and the small effective area of the slotted 1-D PC ...
Shuntaro Makino +2 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source

