Results 61 to 70 of about 419,592 (307)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

February 2010 Newsletter [PDF]

, 2010
Issue Highlights: Interview with IWU 2004 Graduate Joel Brigham Goggles, Grad School and Great ...
Career Center, Illinois Wesleyan University
core   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

September 2012 Newsletter [PDF]

, 2012
Issue Highlights: Career Profile of Alumni Communications Specialists: Joshua Butts \u2701, Jessica Wiley \u2708, Tracy Lytwyn \u2712 It\u27s Fair Season...Time to Gear Up! Why Consider Grad School?
Career Center, Illinois Wesleyan University
core   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

A study on the formation of environmental recognition by dwelling unit location and residential floor in collective housing in a super‐high‐rise building

Japan Architectural Review, 2019
In Japan, a housing plan has been established involving mainly high‐rise housing and standardization. However, there have been few analyses and studies of the relationship and harmony between people and the natural environment based on the relationship ...
Shichun Zong, Hirotomo Ohuchi, Toshihiro Kimura, Satoshi Yamada   +3 more
doaj   +1 more source

The Cowl - v.82 - n.24 - May 3, 2018 [PDF]

, 2018
The Cowl - student newspaper of Providence College. Volume 82, Number 24 - May 3, 2018.

core   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Public Opinion Poll: Executive Summary [PDF]

, 2006
Outlines survey findings on Americans' views on college sports, including commercialization, professionalization, coaches' salaries, athletes' welfare, effects on other departments, and links between athletics success, expenses, and alumni ...

core  

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source