Results 101 to 110 of about 987,516 (263)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Formando futuros maestros: observando las aulas de institutos superiores pedagógicos públicos [PDF]

, 2008
Aborda el tema de la formación de docentes en instituciones de educación superior en cinco regiones del país: Cusco, Cajamarca, Piura, Tacna y San Martín. La investigación sobre la que nos basamos fue parte de un estudio más amplio, realizado en el marco
Ames, Patricia, Ucelli, Francesca, Uccelli, Francesca   +2 more
core  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Sobre los determinantes étnico-culturales de la inequidad en salud materno-infantil en el Perú [PDF]

, 2011
En el Perú, la única información relacionada que se incluye en los cuestionarios de las encuestas y censos es el auto-reporte de la lengua materna de los entrevistados.
Valdivia, Martín
core  

Momordicae Semen: A Review of Phytochemistry, Pharmacology, Toxicology, Herbal Processing, Clinical Applications, and Q-Markers Prediction

Drug Design, Development and Therapy
Xin Deng,1 Yanmei Liu,1 Xiaoli Zhu,1 Hui Zhu,1 Cheng Huang,1 Yan Hong,1,2 Deling Wu,2 Yanquan Han1– 3 1Grade Three-Level Laboratory of TCM Preparation, State Administration of Traditional Chinese Medicine, The First Affiliated Hospital of Anhui ...
Deng X, Liu Y, Zhu X, Zhu H, Huang C, Hong Y, Wu D, Han Y   +7 more
doaj  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Educación superior en el Perú: tendencias de la demanda y la oferta [PDF]

, 2008
Se analiza la evolución y composición de los postulantes e ingresantes a universidades e institutos de educación superior. Se analiza luego la evolución y la composición de la matrícula, que, junto con los ingresantes, reflejan también la capacidad de la
Díaz, Juan José
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

The Cost of Grade Retention [PDF]

This paper uses administrative longitudinal micro data on the universe of Junior High school students in Uruguay to measure the effect of grade failure on students' subsequent school outcomes.
Marco Manacorda
core