Results 51 to 60 of about 65,653 (268)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

High-Power Continuous-Wave Directly-Diode-Pumped Fiber Raman Lasers

Applied Sciences, 2015
We describe novel fiber Raman lasers pumped directly by spectrally combined high power multimode laser diodes at 975 nm and emitting at 1019 nm. With a commercial multimode graded-index fiber, we reached 20 W of laser output power with a record slope ...
Tianfu Yao, Achar V. Harish, Jayanta K. Sahu, Johan Nilsson   +3 more
doaj   +1 more source

On the Digital Holographic Interferometry of Fibrous Material, I. Optical Properties of Polymer and Optical Fibers

, 2012
The digital holographic interferometry (DHI) was utilized for investigating the optical properties of polymer and optical fibers. The samples investigated here were polyvinylidene fluoride (PVDF) polymer fiber and graded-index (GRIN) optical fiber.
Barakat, C. von Kopylow, Chengand, de Angelis, El-Dessouky, El-Morsy, Gabor, H.M. El-Dessouky, Hamza, Hamza, Hamza, Hamza, Hibino, Hossain, K.M. Yassien, Kreis, Liu, M. Agour, Pluta, Pluta, Rappaz, Schnars, Schnars, Schnars, Simmens, Stetson, Surrel, Wahba, Yaroslavsky, Yassien, Zanger, Zhang   +31 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Numerical Analysis of Optical Fiber Refractive Index in the Miniaturized Graded‐Index Fiber Probe

Engineering Reports
We analyze the impact of the refractive index of optical fibers on the focusing properties of a miniaturized graded‐index (GRIN) fiber probe. The ABCD ray transfer matrix and characteristic parameters are employed to characterize the working distance ...
Shubo Bi, Shuaishuai Zhang, Hongying Tang, Zhanyuan Chang, Wenjing Ma, Hairong Zhu   +5 more
doaj   +1 more source

Generation of Narrow Modes in Random Raman Fiber Laser Based on Multimode Fiber

Photonics, 2023
We present a new design of a random Raman fiber laser based on a graded-index multimode fiber as the media composing the cavity that allows the generation of narrow spectral lines.
Ilya D. Vatnik, Oleg A. Gorbunov, Dmitry V. Churkin   +2 more
doaj   +1 more source

An index theorem in differential K-theory [PDF]

, 2010
Let X --> B be a proper submersion with a Riemannian structure. Given a differential K-theory class on X, we define its analytic and topological indices as differential K-theory classes on B.
Freed, Daniel S., Lott, John
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Theory of cw Raman oscillation in optical fibers [PDF]

, 1979
A theory for Raman fiber laser oscillators is presented. The Stokes output and the residual pump power are shown to be calculable from a knowledge of the input pump power and the fiber characteristics. The evolution of the pump and the Stokes waves along
AuYeung, John, Yariv, Amnon
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source