Results 121 to 130 of about 450,444 (294)

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

pi-Regularity of Semigroup Graded Rings

open access: yes, 2002
The notion of pi-regularity is a generalization of von Neumann regularity. In this paper we begin our investigation of pi-regular and strongly pi-regular semigroup graded rings.
Hema Gopalakrishnan   +1 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Analyzing the nonlinear torsional buckling and post-buckling of ES-FG porous cylindrical shells in thermal environment using FSDT in terms of the displacement components

open access: yesVietnam Journal of Mechanics
The main aim of this paper is to investigate the nonlinear buckling and post-buckling of eccentrically stiffened sandwich functionally graded porous (FGP) cylindrical shells surrounded by elastic foundations in thermal environments and under torsional ...
Pham Van Hoan   +3 more
doaj   +1 more source

On Graded Rings, II ($\mathbf{Z}^n$-graded rings)

open access: yesTokyo Journal of Mathematics, 1978
GOTO, Shiro, WATANABE, Keiichi
openaire   +3 more sources

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Nonlinear Analysis on Buckling and Postbuckling of Stiffened FGM Imperfect Cylindrical Shells Filled Inside by Elastic Foundations in Thermal Environment Using TSDT

open access: yesLatin American Journal of Solids and Structures
The main aim of this paper is to investigate analytically nonlinear buckling and post-buckling of functionally graded stiffened circular cylindrical shells filled inside by Pasternak two-parameter elastic foundations in thermal environments and under ...
Pham Minh Vuong, Dao Van Dung
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Gorenstein rings and Kustin-Miller unprojection [PDF]

open access: yes
Chapter 1 briefly describes the motivation for the thesis and presents some background material. Chapter 2 develops the foundations of the theory of unprojection in the local and projective settings.
Papadakis, Stavros
core  

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