Results 111 to 120 of about 11,543 (300)

Commutative graded-n-coherent and graded valuation rings

open access: yes, 2022
Let R = ⊕α∈GRα be a commutative ring with unity graded by an arbitrary grading commutative monoid G. For each positive integer, the notions of a graded-n-coherent module and a graded-n-coherent ring are introduced.
TEKİR, ÜNSAL
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Epsilon-strongly graded rings, separability and semisimplicity

open access: yes, 2018
We introduce the class of epsilon-strongly graded rings and show that it properly contains both the class of strongly graded rings and the class of unital partial crossed products.
Öinert, Johan,   +2 more
core   +1 more source

Generalized rees rings and arithmetical graded rings

open access: yesJournal of Algebra, 1983
0. INTRODUCTION In this paper we study graded rings with an arithmetical ideal theory for the graded ideals, e.g., Gr-Dedekind and Gr-principal ideal rings. If these rings are positively graded rings, then the structure of Gr-Dedekind and of Gr-principal ideal rings is easily investigated and it is much like the structure of the ungraded equivalents ...
openaire   +2 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

The graded structure of algebraic Cuntz-Pimsner rings

open access: yes, 2020
The algebraic Cuntz-Pimsner rings are naturally $\mathbb{Z}$-graded rings that generalize both Leavitt path algebras and unperforated $\mathbb{Z}$-graded Steinberg algebras.
Lännström, Daniel   +1 more
core   +1 more source

Dirac geometry II: coherent cohomology

open access: yesForum of Mathematics, Sigma
Dirac rings are commutative algebras in the symmetric monoidal category of $\mathbb {Z}$ -graded abelian groups with the Koszul sign in the symmetry isomorphism.
Lars Hesselholt, Piotr Pstrągowski
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

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