Results 91 to 100 of about 469,261 (297)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Epsilon-strongly graded rings, separability and semisimplicity

, 2018
We introduce the class of epsilon-strongly graded rings and show that it properly contains both the class of strongly graded rings and the class of unital partial crossed products.
Öinert, Johan,, Nystedt, Patrik,, Pinedo, Héctor,   +2 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

The Category $\mathfrak{G}$-GrR-Mod and Group Factorization

Mathematics
In this work, we use the concept of G-weak graded rings and G-weak graded modules, which are based on grading by a set G of left coset representatives for the left action of a subgroup H of a finite X on X, to define the conjugation action of the set G ...
Rahmah Al-Omari, Mohammed Al-Shomrani
doaj   +1 more source

The graded Jacobson radical of associative rings

, 2009
We introduce a consistent definition for the graded Jacobson radical for group graded rings without unity. We compare the graded Jacobson radical for rings with unity and those without.
Barry Gardner (14737198), Plant, A (15524909)   +1 more
core  

Haploidentical Hematopoietic Cell Transplantation for Infants With X‐Linked Severe Combined Immunodeficiency Using Post‐Transplant Cyclophosphamide

Pediatric Blood &Cancer, EarlyView.
Shuhei Takahashi, Akito Kawachi, Dan Tomomasa, Eri Watanabe, Yuji Fujita, Yuya Sato, Masahiro Sekiguchi, Kentaro Watanabe, Moe Hidaka, Akihiro Hoshino, Takahiro Kamiya, Masatoshi Takagi, Hirokazu Kanegane, Motohiro Kato   +13 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Derived equivalences of upper-triangular ring spectra via lax limits

Comptes Rendus. Mathématique
We extend a theorem of Ladkani concerning derived equivalences between upper-triangular matrix rings to ring spectra. Our result also extends an analogous theorem of Maycock for differential graded algebras.
Jasso, Gustavo
doaj   +1 more source

A theory of grade for commutative rings [PDF]

Proceedings of the American Mathematical Society, 1972
A theory of grade is developed using R-sequences, the Koszul complex and standard homological algebra. Most results of interest are for finitely generated ideals.
openaire   +2 more sources

On primitive ideals in graded rings [PDF]

, 2008
Let R = circle plus(infinity)(i=1) Ri be a graded nil ring. It is shown,that primitive ideals in R are homogeneous. Let A = circle plus(infinity)(i=1) Ai be a graded non-PI just-infinite dimensional algebra and let I be a prime ideal in A.
Smoktunowicz, Agata
core   +1 more source