Results 91 to 100 of about 3,741,721 (286)

Comparative analysis of asbestos body and fiber content in formalin-fixed vs. paraffin-embedded lung tissue

Frontiers in Public Health
IntroductionAsbestos body and fiber burdens may be determined using different preparations of lung tissue. Paraffin-embedded tissue requires more complex steps than formalin-fixed tissue.
Barbara K. Kuhn, Bart Vrugt, Bart Vrugt, Alex Low, Julie E. Goodman, Richard Attanoos   +5 more
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Passive seismic data processing methods to identify contrast intrasalt interlayers in the geological section of the Astrakhan Arch

Georesursy
The article examines the problem of processing microseismic noise (MN) to identify and evaluate occurrence depth of contrasting geological objects – intersalt interlayers with a potentially high formation pressure.
E. V. Biryaltsev, A. A. Vikhoreva, V. A. Zakharchuk, A. Yu. Komarov, V. V. Pykhalov, O. V. Tinakin   +5 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Nonlinear Analysis of the Effects of Socioeconomic, Demographic, and Technological Factors on the Number of Fatal Traffic Accidents

Safety
This study explores the complex connections among various socioeconomic, demographic, and technological aspects and their impact on fatal traffic accidents.
Nassim Sohaee, Shahram Bohluli
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Source Tracing of PM2.5 in a Metropolitan Area Using a Low-Cost Air Quality Monitoring Network: Case Study of Denver, Colorado, USA

Atmosphere
Air quality assessments often require source apportioning of the air pollutants observed at the receptor site. Conventional source apportionment models are subject to high uncertainties due to the lack of accurate emission profiles of all the ...
Nima Afshar-Mohajer, Mirella Shaban
doaj   +1 more source

Function Analysis of the Euclidean Distance between Probability Distributions

Entropy, 2018
Minimization of the Euclidean distance between output distribution and Dirac delta functions as a performance criterion is known to match the distribution of system output with delta functions.
Namyong Kim
doaj   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

gradient

, 2014
Citation: 'gradient' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.G02669 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
  +5 more sources