Results 81 to 90 of about 3,790,217 (289)
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Competitive Gradient Descent [PDF]
, 2019 We introduce a new algorithm for the numerical computation of Nash equilibria of competitive two-player games. Our method is a natural generalization of gradient descent to the two-player setting where the update is given by the Nash equilibrium of a ...
Anandkumar, Anima, Schäfer, Florian
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Oilseeds and fats, crops and lipids, 2017 La pollinisation entomophile du tournesol est souvent mentionnée comme un facteur contribuant au rendement et à la qualité de cette culture. Alors que les rendements stagnent depuis une trentaine d'années en France, l'amélioration de la pollinisation des
Fougeroux André +8 more
doaj +1 more source
In this article I introduce a dynamic interpretation of the gradient of a graph which leads naturally into the notion of ...
Tall, David
core
CoRR, 2016 We propose a novel coding theoretic framework for mitigating stragglers in distributed learning. We show how carefully replicating data blocks and coding across gradients can provide tolerance to failures and stragglers for Synchronous Gradient Descent. We implement our schemes in python (using MPI) to run on Amazon EC2, and show how we compare against
Rashish Tandon +3 more
openaire +2 more sources
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
IEEE Transactions on Signal ProcessingDirectly parameterizing and learning gradients of functions has widespread significance, with specific applications in inverse problems, generative modeling, and optimal transport. This paper introduces gradient networks (GradNets): novel neural network architectures that parameterize gradients of various function classes.
Shreyas Chaudhari +2 more
openaire +2 more sources
Journal of Physics A: Mathematical and Theoretical, 2008 We define gradient networks as directed graphs formed by local gradients of a scalar field distributed on the nodes of a substrate network G. We derive an exact expression for the in-degree distribution of the gradient network when the substrate is a binomial (Erdos-Renyi) random graph, G(N,p).
Toroczkai, Zoltan +4 more
openaire +2 more sources