Results 61 to 70 of about 3,741,721 (286)
Burgers Turbulence with Large-scale Forcing
, 1998 Burgers turbulence supported by white-in-time random forcing at low wavenumbers is studied analytically and by computer simulation. It is concluded that the probability density Q of velocity gradient displays four asymptotic regimes at very large ...
Goto, Toshiyuki +3 more
core +2 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Gradient estimates and Harnack inequalities of a parabolic equation under geometric flow
, 2019 In this paper, we consider a manifold evolving by a general geometric flow and study parabolic equation \[ (\Delta -q(x,t)-\partial_t)u(x,t)=A(u(x,t)),\quad (x,t)\in M\times [0,T].
Zhao, Guangwen
core +1 more source
Gradient Flows, Second-Order Gradient Systems and Convexity [PDF]
SIAM Journal on Optimization, 2018 We disclose an interesting connection between the gradient flow of a $\mathcal{C}^2$-smooth function $ $ and evanescent orbits of the second order gradient system defined by the square-norm of $\nabla $, under adequate convexity assumption. As a consequence, we obtain the following surprising result for two $\mathcal{C}^2$, convex and bounded from ...
Boulmezaoud, Tahar +2 more
openaire +4 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Competitive Gradient Descent [PDF]
, 2019 We introduce a new algorithm for the numerical computation of Nash equilibria of competitive two-player games. Our method is a natural generalization of gradient descent to the two-player setting where the update is given by the Nash equilibrium of a ...
Anandkumar, Anima, Schäfer, Florian
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Hardware-Based Sobel Gradient Computations for Sharpness Enhancement
International Journal of Technology, 2019 The majority of imaging systems are software based; they require some kind of microprocessor or microcontroller for the imaging algorithms to run. As the speed requirements of imaging and communications systems increase, the need for more hardware ...
Daniel Cheok Kiang Kho +2 more
doaj +1 more source
Hybrid Deterministic-Stochastic Methods for Data Fitting
, 2011 Many structured data-fitting applications require the solution of an optimization problem involving a sum over a potentially large number of measurements.
Kumar S. +5 more
core +4 more sources