Results 91 to 100 of about 2,990,696 (280)
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Brain Myelin Covariance Networks: Gradients, Cognition, and Higher-Order Landscape
Myelin is essential for efficient neural signaling and can be quantitatively evaluated using the T1-weighted/T2-weighted (T1w/T2w) ratio as a proxy for regional myelin content.
Huijun Wu +6 more
doaj +1 more source
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Recoloring Cartoon Images Based on Palette Mapping Using K-Means Clustering and Gradient Analysis
This study introduces a palette-based method for the recolorization of cartoon images by combining the k-means clustering algorithm and gradient analysis. The method aims to preserve the visual identity of the original image while allowing flexibility in
Alun Sujjada +3 more
doaj +1 more source
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
RESEARCH ON MECHANICAL PROPERTIES OF GRADIENT LATTICE STRUCTURES BASED ON VORONOI METHOD (MT)
By designing structures with different gradients, the strength of lattice structure can be improved, and its mechanical properties such as impact resistance, energy absorption and vibration reduction can be improved.
LIN Wei, YANG FengShuang, SHI YingYu
doaj
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Distributed non-singular dislocation technique for cracks in strain gradient elasticity
The mode III fracture analysis of a cracked graded plane in the framework of classical, first strain gradient, and second strain gradient elasticity is presented in this paper.
Mousavi S. Mahmoud +2 more
doaj +1 more source
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source

