Results 61 to 70 of about 23,928,830 (244)

A Reliable Health Indicator for Fault Prognosis of Bearings

Sensors, 2018
Estimation of the remaining useful life (RUL) of bearings is important to avoid abrupt shutdowns in rotary machines. An important task in RUL estimation is the construction of a suitable health indicator (HI) to infer the bearing condition.
Bach Phi Duong, Sheraz Ali Khan, Dongkoo Shon, Kichang Im, Jeongho Park, Dong-Sun Lim, Byungtae Jang, Jong-Myon Kim   +7 more
doaj   +1 more source

Gradient pursuits [PDF]

, 2008
Sparse signal approximations have become a fundamental tool in signal processing with wide ranging applications from source separation to signal acquisition.
Blumensath, T., Davies, Michael; id_orcid, Davies, M.E.   +2 more
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Spectral Adaptive Dropout: Frequency-Based Regularization for Improved Generalization

Information
Deep neural networks are often susceptible to overfitting, necessitating effective regularization techniques. This paper introduces Spectral Adaptive Dropout, a novel frequency-based regularization technique that dynamically adjusts dropout rates based ...
Zhigao Huang, Musheng Chen, Shiyan Zheng
doaj   +1 more source

A generalization of Onsager's reciprocity relations to gradient flows with nonlinear mobility [PDF]

, 2015
Onsager's 1931 `reciprocity relations' result connects microscopic time-reversibility with a symmetry property of corresponding macroscopic evolution equations.
Mielke, A, Mielke, A., Renger, D R Michiel, Renger, D. R. Michiel, Peletier, Mark A., Peletier, M.A., Mielke, Alexander, Peletier, MA Mark, Renger, DRM Michiel, Renger, D.R.M.   +9 more
core   +3 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Soil Nutrients in Sandy Plantations Are Related to the Species, Diameter at Breast Height or at Base, and Distance from the Tree Base in Horqin

Land
Correctly understanding existing plantations and improving the cycles and effects of ecological restoration in sandy areas have become important scientific issues. Consequently, we selected different diameters at breast height (DBHs) for Populus spp. and
Hongshun Liu, Rencang Bu, Yu Chang, Li Qi, Chang Chang, Zhibin Zhang, Lujia Zhao   +6 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source