Results 61 to 70 of about 2,990,696 (280)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
A Fast First-Order Optimization Approach to Elastoplastic Analysis of Skeletal Structures
, 2016 It is classical that, when the small deformation is assumed, the incremental analysis problem of an elastoplastic structure with a piecewise-linear yield condition and a linear strain hardening model can be formulated as a convex quadratic programming ...
Kanno, Yoshihiro
core +1 more source
Conjugate gradient methods in confirmatory factor analysis [PDF]
Computational Statistics & Data Analysis, 1994 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Jamshardian, Mortaza, Jennrich, Robert
openaire +2 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
A Reliable Health Indicator for Fault Prognosis of Bearings
Sensors, 2018 Estimation of the remaining useful life (RUL) of bearings is important to avoid abrupt shutdowns in rotary machines. An important task in RUL estimation is the construction of a suitable health indicator (HI) to infer the bearing condition.
Bach Phi Duong +7 more
doaj +1 more source
Complete gradient-LC-ESI system on a chip for protein analysis [PDF]
, 2005 This paper presents the first fully integrated gradient-elution liquid chromatography-electrospray ionization (LC-ESI) system on a chip. This chip integrates a pair of high-pressure gradient pumps, a sample injection pump, a passive mixer, a packed ...
Lee, T. D. +3 more
core
Sharp pointwise gradient estimates for Riesz potentials with a bounded density
, 2018 We establish sharp inequalities for the Riesz potential and its gradient in $\mathbb{R}^{n}$ and indicate their usefulness for potential analysis, moment theory and other applications.Comment: 14 pages, submitted to Analysis and Mathematical ...
Tkachev, Vladimir G.
core +1 more source
Analysis of monotone gradient methods
Journal of Industrial & Management Optimization, 2005 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Dai, Yuhong, Yuan, Yaxiang
openaire +2 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source