Results 111 to 120 of about 1,712,958 (251)

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Lung Stereotactic Body Radiation Therapy (SBRT) dose gradient and PTV volume: a retrospective multi-center analysis

Radiation Oncology, 2019
Background The treatment of lung lesions with stereotactic body radiation therapy calls for highly conformal dose, which is evaluated by a number of metrics. Lung stereotactic body radiation therapy clinical trials constrain a plans gradient index.
David Hoffman, Irena Dragojević, Jeremy Hoisak, David Hoopes, Ryan Manger   +4 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

DESTRUCTION OF FERROMAGNETIG MATERIAL PARTICLES IN MAGNETOVIBRATING LAYER WITH HIGH POROSITY

Вестник Донского государственного технического университета, 2018
The dependence of fineness ratio of magnetic material powders in the magnetovibrating layer on the gradient of magnetic field induction is analyzed.
Yury M. Vernigorov, Natalia N. Frolova
doaj  

Evolution of the Dependence of Residual Lifetimes [PDF]

, 2012
We investigate the dependence properties of a vector of residual lifetimes by means of the copula associated with the conditional distribution function.
Durante F, Fabrizio Durante, Rachele Foschi, Durante, Fabrizio, Foschi R, Foschi, Rachele, Moewes, C., Grzegorzewski, P., Christian Moewes, Olgierd Hryniewicz, Sabo M, B. Vantaggi, SALICONE, SIMONA, Gil Álvarez, María Ángeles, Kruse, R., Berthold, Michael, Rudolf Kruse, Małgorzata Gil, Moewes, Christian, FERRERO, ALESSANDRO, Przemysław Grzegorzewski, Antoine, Violaine, Michael R. Berthold, Hryniewicz, Olgierd, Gil, María, Destercke, Sébastien, Grzegorzewski, Przemysław, Kruse, Rudolf, PRIOLI, MARCO, Foscolo E, Berthold, M. R., Hryniewicz, O.   +31 more
core   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

DESTRUCTION OF FERROMAGNETIG MATERIAL PARTICLES IN MAGNETOVIBRATING LAYER WITH HIGH POROSITY

Advanced Engineering Research, 2011
The dependence of fineness ratio of magnetic material powders in the magnetovibrating layer on the gradient of magnetic field induction is analyzed.
Yury M. Vernigorov, Natalia N. Frolova
doaj  

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

On the strain gradient bending deformations

Journal of the Mechanical Behavior of Materials, 2013
Bending deformations are reviewed in the context of strain gradient linear elasticity, considering the complete set of strain gradient components. It is well understood that conventional bending deformations depend on the collective uniaxial extension of
Lazopoulos Konstantinos A., Lazopoulos Anastasios K.   +1 more
doaj   +1 more source