Results 131 to 140 of about 3,188,796 (338)

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Latitudinal gradients of cosmic rays and the polarity reversal of the heliospheric magnetic field: A preliminary evaluation [PDF]

open access: yes
Within the statistical limits imposed by the currently available data and the noise inherent in the determination of the latitudinal gradient, no evidence for the expected change in the latitudinal gradient from pre-1980 to post-1980 epochs can be found.
Garcia-Munoz, M.   +3 more
core   +1 more source

Grain size and compositional gradient dependence of thermoelectric performance for Cu3−xNixSbSe4 materials

open access: yesResults in Physics, 2021
The ternary Cu3SbSe4 thermoelectric material with diamond-like structure exhibit good thermoelectric performance in the middle temperature region.
Lin Bo   +7 more
doaj  

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

DESTRUCTION OF FERROMAGNETIG MATERIAL PARTICLES IN MAGNETOVIBRATING LAYER WITH HIGH POROSITY

open access: yesAdvanced Engineering Research, 2011
The dependence of fineness ratio of magnetic material powders in the magnetovibrating layer on the gradient of magnetic field induction is analyzed.
Yury M. Vernigorov, Natalia N. Frolova
doaj  

Distribution of thermal characteristics in the north-west part of the near-axial zone of the Dnieper-Donets basin

open access: yesДоповiдi Нацiональної академiї наук України, 2019
The geothermal gradient and heat flow distributions on fields at the axial part of the south-western side of the Dnieper-Donets basin are analyzed. The distributions of geothermal parameters on gas and oil fields are compared.
A.P. Usenko
doaj   +1 more source

The dependence of the gradients of oxygen and nitrogen-to-oxygen on stellar age in MaNGA galaxies [PDF]

open access: bronze, 2021
I. A. Zinchenko   +5 more
openalex   +1 more source

Plant–soil feedback links negative distance dependence and light gradient partitioning during seedling establishment

open access: yes, 2013
Tree species coexistence has often been explained through either negative distance-dependent/density-dependent (NDD) mortality or resource-based niche partitioning.
Sarah McCarthy-Neumann, I. Ibáñez
semanticscholar   +1 more source

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