Results 51 to 60 of about 172,487 (303)

Scale-Dependent Definitions of Gradient and Aspect and their Computation [PDF]

open access: yes, 2006
In order to compute lines of constant gradient and areas of constant aspect on a terrain, we introduce the notion of scale dependent local gradient and aspect for a neighborhood around each point of a terrain. We present three definitions for local gradient and aspect, and give efficient algorithms to compute them.
Iris Reinbacher   +2 more
openaire   +3 more sources

Strain-gradient elasticity and gradient-dependent plasticity with hierarchical refinement of NURBS [PDF]

open access: yesFinite Elements in Analysis and Design, 2019
Higher-order strain-gradient models are relevant for engineering materials which exhibit size-dependent behaviour as observed from experiments. Typically, this class of models incorporate a length scale - related to micro-mechanical material properties - to capture size effects, remove stress singularities, or regularise an ill-posed boundary value ...
Kolo, I., Chen, L., de Borst, R.
openaire   +2 more sources

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

Complicated dynamics of parabolic equations with simple gradient dependence [PDF]

open access: yesTransactions of the American Mathematical Society, 1998
Summary: Let \(\Omega\subset\mathbb{R}^2\) be a smooth bounded domain. Given positive integers \(n,k\) and \(q_l\leq l\), \(l=1,\dots,k\), consider the semilinear parabolic equation \[ u_{t}= u_{xx}+ u_{yy}+ a(x,y)u+ \sum_{l=1}^k a_l(x,y) u^{l-q_{l}} (u_{y})^{q_{l}}, \quad t>0,\;(x,y)\in \Omega,\tag{E} \] \[ u=0, \qquad t>0,\;(x,y)\in \partial \Omega. \
PRIZZI, Martino, RYBAKOWSKI K. P.
openaire   +3 more sources

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

Atomistic simulations of plasticity heterogeneity in gradient nano-grained FCC metals

open access: yesMaterials & Design, 2022
Gradient nano-grained (GNG) metals are an emerging class of heterogeneous structured materials with extraordinary mechanistic performances and unnatural plasticity mechanisms, which are unachievable in traditional homogeneous nanocrystalline metals. Here,
Like Xu   +3 more
doaj   +1 more source

Limit theorems for gradient-dependent elastoplastic geomaterials

open access: yesInternational Journal of Solids and Structures, 2007
AbstractIn this paper, the limit theorems proposed by Drucker and co-workers are reformulated to address a class of gradient-dependent elastoplastic geomaterials. The gradient effects are accounted for by incorporating strain gradients and their conjugate higher-order stresses into the constitutive descriptions. Gradient-dependent equilibrium equations
Zhao, Jidong   +3 more
openaire   +3 more sources

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

open access: yesFEBS Letters, EarlyView.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi   +5 more
wiley   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Proton Gradients and Proton-Dependent Transport Processes in the Chloroplast [PDF]

open access: yesFrontiers in Plant Science, 2016
Proton gradients are fundamental to chloroplast function. Across thylakoid membranes, the light induced -proton gradient is essential for ATP synthesis. As a result of proton pumping into the thylakoid lumen, an alkaline stromal pH develops, which is required for full activation of pH-dependent Calvin Benson cycle enzymes.
Höhner, Ricarda   +3 more
openaire   +5 more sources

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