Results 51 to 60 of about 192,182 (265)
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
In our paper we address the thermoelasticity theory of the strain gradient. First, we define the mixed problem with initial and boundary data in this context.
Marin Marin, Sorin Vlase, Ioan Tuns
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Nodal solutions for Neumann systems with gradient dependence
We consider the following convective Neumann systems: ( S ) { − Δ p 1 u 1 + | ∇ u 1 | p 1 u 1 + δ 1 = f 1 ( x , u 1 , u 2 , ∇ u 1 , ∇ u 2 ) in Ω , − Δ p 2 u 2 + | ∇ u 2 | p 2 u 2 + δ 2 = f 2 ( x , u 1 , u 2 , ∇ u 1 , ∇ u 2 ) in Ω , | ∇ u 1 | p 1 − 2 ...
Kamel Saoudi +2 more
doaj +1 more source
Resonant optical gradient force interaction for nano-imaging and -spectroscopy
The optical gradient force provides optomechanical interactions, for particle trapping and manipulation, as well as for near-field optical imaging in scanning probe microscopy.
Honghua U Yang, Markus B Raschke
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
The effect of torsional prestrain gradient on the size dependence of initial yielding during subsequent tension of Cu-Mn single crystals is investigated experimentally.
Eleftheriadis Iordanis +2 more
doaj +1 more source
Range dependent phase gradient autofocus [PDF]
The Phase Gradient Autofocus (PGA) algorithm has been widely used in spotlight synthetic aperture radar (SAR) to remove motion-induced blurs in the images. The PGA algorithm has been proven to be a superior autofocus method. PGA assumes a narrow beam, which is valid for most SAR systems.
D.G. Thompson +4 more
openaire +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source

