Results 51 to 60 of about 1,712,958 (251)

On a Neumann Problem with an Intrinsic Operator

open access: yesAxioms
This paper investigates the existence and location of solutions for a Neumann problem driven by a (p,q) Laplacian operator and with a reaction term that depends not only on the solution and its gradient but also incorporates an intrinsic operator, which ...
Dumitru Motreanu, Angela Sciammetta
doaj   +1 more source

On a parabolic–elliptic system with gradient dependent chemotactic coefficient [PDF]

open access: yesJournal of Differential Equations, 2018
We consider a second order PDEs system of Parabolic-Elliptic type with chemotactic terms. The system describes the evolution of a biological species "$u$" moving towards a higher concentration of a chemical stimuli "$v$" in a bounded and open domain of $ \mathcal{R}^N$. In the system considered, the chemotaxis sensitivity depends on the gradient of $v$,
Mihaela Negreanu, J. Ignacio Tello
openaire   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Semilinear elliptic equations with dependence on the gradient via Mountain-Pass techniques [PDF]

open access: yes, 2004
A class of semilinear elliptic equations with dependence on the gradient is considered. The existence of a positive and a negative solution is stated through an iterative method based on Mountain Pass ...
Matzeu, M   +6 more
core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Nonzero Positive Solutions of Elliptic Systems with Gradient Dependence and Functional BCs

open access: yesAdvanced Nonlinear Studies, 2020
We discuss, by topological methods, the solvability of systems of second-order elliptic differential equations subject to functional boundary conditions under the presence of gradient terms in the nonlinearities.
Biagi Stefano   +2 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Model2-gradient-PSG-GN inversion

open access: yes, 2023
The gradient distribution of PSG-GN inversion.
Xiuyan Ren (14583824)
core   +1 more source

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