Results 81 to 90 of about 192,182 (265)
Nonlinear Robin problems with unilateral constraints and dependence on the gradient
Electronic Journal of Differential Equations, 2018 We consider a nonlinear Robin problem driven by the p-Laplacian, with unilateral constraints and a reaction term depending also on the gradient (convection term). Using a topological approach based on fixed point theory (the Leray-Schauder alternative
Nikolaos S. Papageorgiou +2 more
doaj
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Radiation Oncology, 2019 Background The treatment of lung lesions with stereotactic body radiation therapy calls for highly conformal dose, which is evaluated by a number of metrics. Lung stereotactic body radiation therapy clinical trials constrain a plans gradient index.
David Hoffman +4 more
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
On the strain gradient bending deformations
Journal of the Mechanical Behavior of Materials, 2013 Bending deformations are reviewed in the context of strain gradient linear elasticity, considering the complete set of strain gradient components. It is well understood that conventional bending deformations depend on the collective uniaxial extension of
Lazopoulos Konstantinos A. +1 more
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
DESTRUCTION OF FERROMAGNETIG MATERIAL PARTICLES IN MAGNETOVIBRATING LAYER WITH HIGH POROSITY
Advanced Engineering Research, 2011 The dependence of fineness ratio of magnetic material powders in the magnetovibrating layer on the gradient of magnetic field induction is analyzed.
Yury M. Vernigorov, Natalia N. Frolova
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
DESTRUCTION OF FERROMAGNETIG MATERIAL PARTICLES IN MAGNETOVIBRATING LAYER WITH HIGH POROSITY
Вестник Донского государственного технического университета, 2018 The dependence of fineness ratio of magnetic material powders in the magnetovibrating layer on the gradient of magnetic field induction is analyzed.
Yury M. Vernigorov, Natalia N. Frolova
doaj
On periodic elliptic equations with gradient dependence
Communications on Pure and Applied Analysis, 2008 We construct entire solutions of $\Delta u=f(x,u,\nabla u)$ which are superpositions of odd, periodic functions and linear ones, with prescribed integer or rational slope.
Berti, M., Matzeu, M., Valdinoci, E.
openaire +4 more sources