Results 111 to 120 of about 36,010,976 (311)

Sensitivity Analysis of Compressive Sensing Solutions

Frontiers in Robotics and AI, 2015
The compressive sensing framework □nds a wide range of applications in signal processing, data analysis and fusion. Within this framework, various methods have been proposed to □nd a sparse solution x from a linear measurement model y = Ax.
Liyi eDai
doaj   +1 more source

Gradient methods of maximization [PDF]

Pacific Journal of Mathematics, 1955
Crockett, Jean Bronfenbrenner, Chernoff, Herman   +1 more
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Applications of Mitscherlich Baule function: a robust regression approach

Research in Statistics
Consistent estimation techniques need to be implemented to obtain robust empirical outcomes which help policymakers formulating public policies. Therefore, Mitscherlich Baule function was implemented using robust regression model based on a growth ...
Rizwan Yousuf, Manish Sharma
doaj   +1 more source

Solution of Optimal Harvesting Problem by Finite Difference Approximations of Size-Structured Population Model

Mathematical and Computational Applications, 2018
We solve numerically a forest management optimization problem governed by a nonlinear partial differential equation (PDE), which is a size-structured population model.
Johanna Pyy, Anssi Ahtikoski, Alexander Lapin, Erkki Laitinen   +3 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Seasonal Analysis of Planetary Boundary Layer and Turbulence in Warsaw, Poland Through Lidar and LES Simulations

Remote Sensing
We analyzed the planetary boundary layer (PBL) characteristics in Warsaw, Poland for a day of summer, autumn, winter, and spring of 2021 by integrating and comparing measured and simulated data.
Rayonil G. Carneiro, Maciej Karasewicz, Camilla K. Borges, Lucja Janicka, Dongxiang Wang, Gilberto Fisch, Iwona S. Stachlewska   +6 more
doaj   +1 more source

Thermophysical Properties Estimation in Annealing Process Using the Iterative Dynamic Programming Method and Gradient Method

Energies, 2019
In annealing, steel coils should be heated and consequently cooled according to the technological prescription defined for the annealed type of steel. It is appropriate to develop the systems and methods for estimation of the steel coil inner temperature
Milan Durdán, Ján Kačur, Marek Laciak, Patrik Flegner   +3 more
doaj   +1 more source