Results 131 to 140 of about 2,146,103 (291)

ASGO: Adaptive Structured Gradient Optimization

39 ...
An, Kang, Liu, Yuxing, Pan, Rui, Ren, Yi, Ma, Shiqian, Goldfarb, Donald, Zhang, Tong   +6 more
openaire   +2 more sources

Intercompartmental communication in senescence

FEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz, Eleanor J. Wind, Jixiang Leng, Myriam Gorospe   +3 more
wiley   +1 more source

Extremely fast-charging lithium ion battery enabled by dual-gradient structure design. [PDF]

Sci Adv, 2022
Lu LL, Lu YY, Zhu ZX, Shao JX, Yao HB, Wang S, Zhang TW, Ni Y, Wang XX, Yu SH.   +9 more
europepmc   +1 more source

Structure Matters: Dynamic Policy Gradient

In this work, we study $γ$-discounted infinite-horizon tabular Markov decision processes (MDPs) and introduce a framework called dynamic policy gradient (DynPG). The framework directly integrates dynamic programming with (any) policy gradient method, explicitly leveraging the Markovian property of the environment.
Klein, Sara, Zhang, Xiangyuan, Başar, Tamer, Weissmann, Simon, Döring, Leif   +4 more
openaire   +2 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Path Generation Strategy and Wire Arc Additive Manufacturing of Large Aviation Die with Complex Gradient Structure. [PDF]

Materials (Basel), 2022
Zhang J, Xiao G, Peng J, Yu Y, Zhou J.
europepmc   +1 more source

Deep Learning–Assisted Differentiation of Four Peripheral Neuropathies Using Corneal Confocal Microscopy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah, Ioannis N. Petropoulos, Mark Stettner, Maryam Ferdousi, Uazman Alam, Nathan Efron, Ahmed Serag, Rayaz A. Malik   +7 more
wiley   +1 more source

Effect of Cold Swaging on the Bulk Gradient Structure Formation and Mechanical Properties of a 316-Type Austenitic Stainless Steel. [PDF]

Materials (Basel), 2022
Panov D, Chernichenko R, Kudryavtsev E, Klimenko D, Naumov S, Pertcev A.   +5 more
europepmc   +1 more source

High Gradient Superconducting RF Structures

, 1998
19th International Linear Accelerator Conference, LINAC 98, Chicago, USA, 23 Aug 1998 - 28 Aug 1998; 59 pp. (1998).
openaire   +2 more sources

Chronological and Spatial Distribution of Skeletal Muscle Fat Replacement in FHL1‐Related Myopathies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Variants in the FHL1 gene cause FHL1‐related myopathies (FHL1‐RMs), a group of neuromuscular disorders with diverse clinical presentations. This study aimed to comprehensively characterize the spatial and temporal patterns of skeletal muscle fat replacement throughout the whole body in FHL1‐RMs, to examine disease progression over ...
Rui Shimazaki, Satoru Noguchi, Hotake Takizawa, Yasushi Oya, Yuji Takahashi, Hirofumi Komaki, Hajime Arahata, Shinichiro Hayashi, Ichizo Nishino   +8 more
wiley   +1 more source