Results 41 to 50 of about 749,068 (264)

Investigation of Mechanical Properties and Microstructural Evolution in Pure Copper with Dual Heterostructures Produced by Surface Mechanical Attrition Treatment

open access: yesMetals
Heterostructured materials consist of heterogeneous zones with dramatic variations in mechanical properties, and have attracted extensive attention due to their superior performance.
Lele Sun   +8 more
doaj   +1 more source

Cortical thickness gradients in structural hierarchies

open access: yesNeuroImage, 2015
MRI, enabling in vivo analysis of cortical morphology, offers a powerful tool in the assessment of brain development and pathology. One of the most ubiquitous measures used-the thickness of the cortex-shows abnormalities in a number of diseases and conditions, but the functional and biological correlates of such alterations are unclear.
Konrad Wagstyl   +3 more
openaire   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

An Innovative Strategy for Achieving Interface Gradient Material Using Co-Deposition Technology

open access: yesNanomaterials
In this study, high-performance SiC whisker (SiCw)-reinforced Cu matrix functionally graded materials (FGMs) were achieved through the synergy of numerical simulation and co-electrodeposition and then successfully applied as the interface of Cu and Si. A
Yanxin Zhang   +4 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Dual-gradient ceramic/aluminum composite structure fabricated by arc additive manufacturing with co-conveying of wire and powder

open access: yesMaterials Research Letters
We employed a novel technique combining wire and powder co-delivery to fabricate a functionally gradient material (FGM) structure consisting of Al-based composites reinforced with alternating TiC and B4C particles.
Jian-Xin Sun   +6 more
doaj   +1 more source

Multiscale Gradients of Corticopontine Structural Connectivity

open access: yesScientific Reports
Abstract The cerebellum’s involvement in a range of cognitive, emotional, and motor processes has become increasingly evident. Given the uniformity of the cerebellar cortex’s cellular architecture its contributions to varied processes are thought be partially mediated by its patterns of reciprocal connectivity with the rest of the brain.
Rousseau, P.   +2 more
openaire   +4 more sources

Gradient-Boosted Based Structured and Unstructured Learning

open access: yes, 2023
We propose two frameworks to deal with problem settings in which both structured and unstructured data are available. Structured data problems are best solved by traditional machine learning models such as boosting and tree-based algorithms, whereas deep learning has been widely applied to problems dealing with images, text, audio, and other ...
Andrea Treviño Gavito   +2 more
openaire   +2 more sources

On the structure of gradient Yamabe solitons [PDF]

open access: yesMathematical Research Letters, 2012
We show that every complete nontrivial gradient Yamabe soliton admits a special global warped product structure with a one-dimensional base. Based on this, we prove a general classification theorem for complete nontrivial locally conformally flat gradient Yamabe solitons.
Cao, Huai-Dong   +2 more
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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