Results 111 to 120 of about 1,429,141 (363)
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Acta Biológica Colombiana, 2002 En el Parque Nacional Natural Chingaza, Cundinamarca, sitio de la quebrada de Piedras Gordas y valles y laderas del río Tunjo, se realizó un estudio de la estructura de dos comunidades vegetales pertenecientes a las especies dominantes de Espeletia ...
Silvio Zuluaga Ramírez
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La vegetación briofítica rupícola en relación con los gradientes altitudinal e hígrico en el Montseny (Barcelona) [PDF]
, 1986 Bryophytic vegetation along an elevation gradient of 1350 m in Montseny has been studied by sampling 36 stones or walls with different moisture index, calculated from the distance to the nearest running water.
Lloret Maya, Francisco
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Revista de la Facultad de Medicina, 1996 Morfógenos, compartimentos y el patrón / Gradientes que organizan el desarrollo temprano / Mutaciones que causan mutaciones / El internet se autocensura?
Facultad de Medicina Revista
doaj
Regulação da resposta imunológica pelas células T no rato: mecanismos de interacção celular.
Acta Médica Portuguesa, 1979 Subpopulações de células T com funções helper ou supressora foram isoladas do baço do rato por fraccionamento em gradientes descontínuos de albumina. O estudo in vitro e in vivo da interacção destas populações celulares sugere a existência de um duplo ...
Benedita Rocha +2 more
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Optimización en tiempo real con disyunciones lógicas: aplicación a sistemas de calor y potencia [PDF]
, 2013 La Optimización en Tiempo Real (RTO) permite operar en cercanías del óptimo económico de una planta, respetando restricciones y respondiendo a cambios en el proceso.
Aguirre, Pio Antonio +2 more
core +2 more sources
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Influence of thermal parameters on microstructure of Al-Cu alloys directionally solidified [PDF]
, 2012 Para investigar la influencia de los parámetros de solidificación sobre la microestructura dendrítica de las aleaciones Al-Cu de diferentes concentraciones se realizaron experiencias con diferentes valores de velocidades de enfriamiento y gradientes de ...
Ares, Alicia Esther +4 more
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