Results 111 to 120 of about 632,931 (308)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

A Wavenumber-Domain Iterative Approach for Rapid 3-D Imaging of Gravity Anomalies and Gradients

open access: yesIEEE Access, 2019
We present a wavenumber-domain iterative approach for rapid 3-D imaging of gravity anomalies and gradients data, which is based on the 3-D mesh model with a flat observational surface.
Yatong Cui, Lianghui Guo
doaj   +1 more source

MIZwally/gradients-and-behavior: v1.0.0

open access: yes
<p>This repository contains code used by Mia Zwally during her time with the Data Science and Sharing Team for the analysis of functional gradients in the Adolescent Brain Cognitive Development study.</p ...
Mia Zwally
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Housing Price Gradients in a Region with One Dominating Center [PDF]

open access: yes
This paper primarily focuses on predicting housing price gradients in a Norwegian region with one dominating center. Spatial separation is represented by a function of the traveling distance from the city center in a traditional hedonic regression ...
Liv Osland   +2 more
core  

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Transforming layered 2D mats into multiphasic 3D nanofiber scaffolds with tailored gradient features for tissue regeneration

open access: yesBMEMat
Multiphasic scaffolds with tailored gradient features hold significant promise for tissue regeneration applications. Herein, this work reports the transformation of two‐dimensional (2D) layered fiber mats into three‐dimensional (3D) multiphasic scaffolds
S. M. Shatil Shahriar   +7 more
doaj   +1 more source

The impact of emotional valence on generalization gradients [PDF]

open access: yes
Generalization enables individuals to respond to novel stimuli based on previous experiences. The degree to which organisms respond is determined by their physical resemblance to the original conditioned stimulus (CS+), with a stronger response elicited ...
Martínez-Tomás, Celia   +5 more
core   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Gradients on Sets

open access: yes, 2018
For a locally Lipschitz continuous function $f:X\to\mathbb{R}$ the generalized gradient $\partial f(x)$ of Clarke is used to develop some (set-valued) gradient on a set $A\subset X$. Existence, uniqueness and some approximation are considered for optimal descent directions on set $A$.
Mankau, Jan, Schuricht, Friedemann
openaire   +3 more sources

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