Results 101 to 110 of about 632,931 (308)
Deci-AI/super-gradients: 3.6.0
<h2>What's Changed</h2> <ul> <li>Fix numpy deprecation warning on creating ragged array when using _pad_image by @BloodAxe in https://github.com/Deci-AI/super-gradients/pull/1632</li> <li>Allow setting per-layer ...
Borys Tymchenko +29 more
core +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
OXYGEN GRADIENTS CAUSE PATTERN ORIENTATION IN DICTYOSTELIUM CELL CLUMPS [PDF]
, 1981 We have investigated the formation of the prestalk-prespore pattern in Dictyottelium discoideum. Pattern formation occurs in clumps of Dictyostelium cells embedded in agar under a 100% oxygen atmosphere.
Sternfeld, John, David, Charles N.
core +1 more source
On the Importance of Countergradients for the Development of Retinotopy: Insights from a Generalised Gierer Model [PDF]
, 2013 During the development of the topographic map from vertebrate retina to superior colliculus (SC), EphA receptors are expressed in a gradient along the nasotemporal retinal axis. Their ligands, ephrin-As, are expressed in a gradient along the rostrocaudal
David C Sterratt +3 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Converting Level Set Gradients to Shape Gradients [PDF]
, 2010 The level set representation of shapes is useful for shape evolution and is widely used for the minimization of energies with respect to shapes. Many algorithms consider energies depending explicitly on the signed distance function (SDF) associated with a shape, and differentiate these energies with respect to the SDF directly in order to make the ...
Chen, Siqi +2 more
openaire +3 more sources
Deci-AI/super-gradients: 3.7.1
<h2>What's Changed</h2> <ul> <li>Fix: added ddp silent if statement before saving checkpoint when resuming by @shaydeci in https://github.com/Deci-AI/super-gradients/pull/1948</li> <li>updated version in notebook and ...
Borys Tymchenko +29 more
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source