Results 51 to 60 of about 16,696,427 (330)

Tackling Evolving Botnet Threats: A Gradual Self-Training Neural Network Approach

open access: yesIEEE Access
Botnets pose a significant challenge to network security but are difficult to detect because of their dynamic and evolving nature, which limits the effectiveness of conventional supervised neural network detection methods.
Ta-Chun Lo   +4 more
doaj   +1 more source

Assessment of Dynamic Bayesian Models for Gas Turbine Diagnostics, Part 2: Discrimination of Gradual Degradation and Rapid Faults

open access: yesMachines, 2021
There are many challenges that an effective diagnostic system must overcome for successful fault diagnosis in gas turbines. Among others, it has to be robust to engine-to-engine variations in the fleet, it has to discriminate between gradual ...
Valentina Zaccaria   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The gradual erosion of the ultra vires doctrine in English company law

open access: yes, 2014
Purpose – The purpose of this paper is to discuss the doctrine of ultra vires and its development over time, which is claimed to be one of gradual erosion. Design/methodology/approach – This paper discusses the doctrine of ultra vires and its development
Nyombi, C., Nyombi, Chrispas
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A robust nonlinear scale space change detection approach for SAR images [PDF]

open access: yes, 2013
In this paper, we propose a change detection approach based on nonlinear scale space analysis of change images for robust detection of various changes incurred by natural phenomena and/or human activities in Synthetic Aperture Radar (SAR) images using ...
Müjdat Çetin   +9 more
core   +1 more source

Impact of Alignment Edits on the Quality of Experience of 360° Videos

open access: yesIEEE Access, 2023
Optimizing user quality of experience (QoE) for 360° videos faces two major roadblocks: inaccurate viewport prediction and viewers missing the plot of a story.
Lucas S. Althoff   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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