Results 51 to 60 of about 2,023,837 (235)

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Brazilian forensic nursing: convergence of goals for the specialty’s next decade

Revista Brasileira de Enfermagem
Objectives: to understand forensic nurses’ perspectives and direct advances in forensic nursing in Brazil. Methods: a qualitative study conducted through semi-structured online interviews between April and May 2023 with 22 forensic nurse specialists ...
Davydson Gouveia Santos, Vanessa Martinhago Borges Fernandes, José Luís Guedes dos Santos, Fábio Silva Rosa, Morgana Oliveira Citolin, Mara Ambrosina de Oliveira Vargas   +5 more
doaj   +2 more sources

Resident perceptions of the impact of duty hour restrictions on resident-attending interactions: an exploratory study

BMC Medical Education, 2017
Background The institution of duty hour reforms by the Accreditation Council for Graduate Medical Education in 2003 has created a learning environment where residents are consistently looking for input from attending physicians with regards to balancing ...
Kristen A. Gerjevic, Marcy E. Rosenbaum, Manish Suneja   +2 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

PANCASILA AS THE PHILOSOPHICAL FOUNDATION OF THE INDONESIAN CURRICULUM

Paradigma: Jurnal Kajian Budaya
Being Indonesia’s philosophical foundation, Pancasila, comprised of five principles, plays a significant role in shaping the country’s education system.
Nurbaya Pulhehe, Babang Robandi
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Mental health burden among unemployed graduate job seekers in Bangladesh: evidence on depression, anxiety, stress, insomnia, and suicidal behavior

Discover Psychology
Background In LMICs like Bangladesh, mental health morbidities such as depression, anxiety, stress, insomnia, and suicidal behavior are becoming a major concern for graduate job seekers. The objective of this study was to compare the levels of depression,
Abdul Muyeed, Md Limon Bhuiyan, Maruf Hasan Rumi, Anup Talukder, Ratul Rahman   +4 more
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

19881007: Graduate School, 1975-1987 [PDF]

, 1988
These items include materials from the office of the Graduate School at Marshall University from 1975-1987. Items were received in 1988 and were processed in 2025 and include notable materials from or about graduate school Deans\u27 Council Meetings ...
Graduate School
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