Results 201 to 210 of about 7,454 (299)
Iduronate 2‐sulfatase (IDS; purple) is expressed as a precursor protein that goes through multiple steps of maturation, modification, and trafficking to become an active lysosomal enzyme that degrades glycosaminoglycans. Our study shows that the transmembrane ubiquitin ligases RNF13 (orange) and RNF167 (pink) heterodimerize, affecting IDS intracellular
Valérie C. Cabana +4 more
wiley +1 more source
Value, Structure, and Curriculum in US Graduate Health Informatics Programs: Cross-Sectional Study. [PDF]
Sawesi S +3 more
europepmc +1 more source
RNF13 regulates the endolysosomal pathway through interaction with the small GTPase Arl8B
The E3 ubiquitin ligase RNF13 functions as a regulatory scaffold, organizing Arl8B‐dependent complexes and tuning downstream signaling that controls endolysosomal organization and trafficking. In this model, wild‐type RNF13 associates with Arl8B on endolysosomes, whereas Arl8B (E22D/F55A) or RNF13 (L244A) variants weaken complex assembly, potentially ...
Audrey M. Sénécal +4 more
wiley +1 more source
Corrigendum: Esports Physical Exercise/Performance Matrix 1.0 Country Factsheets: a protocol for national, regional, and global annual assessment. [PDF]
Long B +4 more
europepmc +1 more source
Lack of Compliance in Gillnet Fisheries Regulations Increases Risk to a Vulnerable Species
ABSTRACT This article presents an analysis of regulatory compliance in a Brazilian gillnet fishery, based on Vessel Monitoring System (VMS) tracking data. Satellite transmissions records, interpreted as proxies for gillnet haulings events, were analyzed and classified using a neural network to assess the level of compliance of the gillnet fleet.
Rodrigo Claudino dos Santos +3 more
wiley +1 more source
Postgraduate medical education in fragile conflict-affected settings: A scoping review. [PDF]
Alomar AA +3 more
europepmc +1 more source
ABSTRACT The infrastructure of precarious work is racialized and gendered, affecting disenfranchised Black women who carry the burden of low paid caregiving within the healthcare system. In South Africa, Community Health Workers, predominantly Black women from marginalized communities, have been vital in providing primary healthcare services at home ...
Sivuyisiwe Wonci
wiley +1 more source

