Results 91 to 100 of about 752,868 (308)

Minimization of maximum amplitude magnification factor in designing double-mass dynamic vibration absorbers (Application of optimality criteria method to parallel and series types)

Nihon Kikai Gakkai ronbunshu, 2017
The optimal design method of double-mass dynamic vibration absorbers (DVAs) is discussed with respect to the minimization of the maximum amplitude magnification factor.
Osamu NISHIHARA
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

The GFPT2/O-GlcNAcylation/c-Myc axis promotes bladder cancer progression

Journal of Translational Medicine
Background Glucose metabolic reprogramming is a hallmark of bladder cancer. However, the exact relationship between glucose metabolism and the onset and progression of bladder cancer remains poorly understood.
Huadong Xie, Tianling Liao, Han Tang, Chengjie Ban, Zhi Cheng, Kangji Liao, Yongpeng Li, Wei Wei, Liquan Zhou, Xianlin Yi   +9 more
doaj   +1 more source

Authentic leadership, empowerment and burnout: a comparison in new graduates and experienced nurses.

Journal of Nursing Management, 2013
AIM To examine the effect of authentic leadership and structural empowerment on the emotional exhaustion and cynicism of new graduates and experienced acute-care nurses.
H. Laschinger, Carol A. Wong, Ashley L. Grau   +2 more
semanticscholar   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

International medical graduates in family medicine in the United States of America: an exploration of professional characteristics and attitudes

Human Resources for Health, 2006
BackgroundThe number of international medical graduates (IMGs) entering family medicine in the United States of America has steadily increased since 1997. Previous research has examined practice locations of these IMGs and their role in providing care to
A. Morris, R. Phillips, G. E. Fryer, L. Green, F. Mullan   +4 more
semanticscholar   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Career adaptability, job search self-efficacy and outcomes: A three-wave investigation among Chinese University Graduates

, 2013
Based on career construction theory, the current research examined the role of career adaptability in Chinese university graduates' job search process (N = 270). Results from a three-wave survey study showed that the four dimension of career adaptability
Yanjun Guan, Hong Deng, Jiaqing Sun, Yanan Wang, Zijun Cai, Lihui Ye, Ruchunyi Fu, Yang Wang, Shu Zhang, Yuhui Li   +9 more
semanticscholar   +1 more source

Recommendations from recent graduates in medicine, nursing and pharmacy on improving interprofessional education in university programs: a qualitative study

BMC Medical Education, 2014
BackgroundInterprofessional education (IPE) has been recognized as an innovative approach for the development of a collaborative, practice-ready health workforce, but is not used consistently in undergraduate health professional programs.
C. Gilligan, S. Outram, T. Levett-Jones
semanticscholar   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source