Results 61 to 70 of about 752,868 (308)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The Capacity of Indonesia as a Source Country in Enabling Trafficking in Person by Devina A Millenia

Contemporary Challenges
This paper examines the analytical discussion that Indonesia, as an origin or source country, has an enabling role in trafficking in person (TIP). It argues that the failure of the government’s institutional and social dimensions in the source countries ...
Devina Millenia
doaj   +1 more source

Purpose-Based Career Coaching as a Strategy for Increasing Employability of Graduates: A Survey Study

International Journal of Home Economics, Hospitality and Allied Research, 2023
This study investigated teachers’ and counsellors’ perception of a purpose-based career coaching as a strategy for increasing employability of graduates in Nigeria.
Mkpoikanke Sunday Otu, Favour Mkpoikanke Otu, Zadrian Ardi   +2 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Maternal and paternal lineage analysis of Island Southeast Asian goats reveals continental propagation routes and introgression through the Indian ocean

Scientific Reports
The Philippines and Indonesia, located at the crossroads of historical human migrations in the Asia-Pacific region, lie in the southeasternmost part of Mainland Southeast Asia. Both countries are recognized as mega-diverse nations, hosting a wide variety
Ryo Masuko, Ayin, Maho Masaoka, Fuki Kawaguchi, Shinji Sasazaki, Muhammad I. A. Dagong, Sri R. A. Bugiwati, Joseph S. Masangkay, Takahiro Yonezawa, Hideyuki Mannen   +9 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Novel cell therapy with ex vivo cultured peripheral blood mononuclear cells significantly impacts angiogenesis in the murine ischemic limb model

Regenerative Therapy
Introduction: Autologous mononuclear cells (MNCs) have been used in vascular regenerative therapy since the identification of endothelial progenitor cells (EPCs).
Satomi Furukawa, Rie Hirano, Ai Sugawara, Satoshi Fujimura, Rica Tanaka   +4 more
doaj   +1 more source

Employability Skills of Higher Education Graduates: Little Consensus on a Much-discussed Subject

, 2016
The expansion of higher education (HE) has given rise to research on skills that smooth transition and benefit the careers of graduates. We examine literature that attempts to inform HE institutions and policy makers about the skills required in the ...
F. Suleman
semanticscholar   +1 more source

The Future of Pediatric Hematology‐Oncology Fellowship Training: Reflections on the American Board of Pediatrics Training Model

Pediatric Blood &Cancer, EarlyView.
Scott C. Borinstein, Scott Moerdler, Alexander A. Boucher, Stacy L. Cooper, Rachel A Egler, Erika Friehling, Richard Ho, Catherine McGuinn, Kathryn S. Sutton, Stacey G. Zahler, Leslie Kersun, Jennifer Kesselheim   +11 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source