Results 101 to 110 of about 179,002 (365)

Increasing the Discovery Power and Confidence Levels of Disease Association Studies: A Survey [PDF]

arXiv, 2017
The majority of common diseases are influenced by multiple genetic and environmental factors such as Cancer. Even though uncovering the main causes of disease is deemed difficult due to the complexity of gene-gene and gene-environment interactions, major research efforts aim at identifying disease risk factors, especially genetic ones.
arxiv  

The combination of sirolimus plus tacrolimus improves outcome after reduced-intensity conditioning, unrelated donor hematopoietic stem cell transplantation compared with cyclosporine plus mycofenolate [PDF]

, 2013
Different types of graft-versus-host disease prophylaxis have been proposed in the setting of reduced intensity and non-myeloablative allogeneic stem cell transplantation.
Caballero, Dolores, Cabrero, Mónica, López Corral, Lucía, Martino, Rodrigo, Martínez, Carmen, Márquez Malaver, Francisco J., Parody, Rocío, Pérez Simón, José Antonio, Sierra, Jordi, Solano, Carlos, Valcárcel, D., Vázquez, Lourdes   +11 more
core   +1 more source

Engineering the Future of Restorative Clinical Peripheral Nerve Surgery

Advanced Healthcare Materials, EarlyView.
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell, Zarina S. Ali, Eric L. Zager, Joseph M. Rosen, Mykhailo M. Tatarchuk, D. Kacy Cullen   +5 more
wiley   +1 more source

The development of nations conditions the disease space [PDF]

arXiv, 2019
Using the economic complexity methodology on data for disease prevalence in 195 countries during the period of 1990-2016, we propose two new metrics for quantifying the relatedness between diseases, or the `disease space' of countries. With these metrics, we analyze the geography of diseases and empirically investigate the effect of economic ...
arxiv  

Pretransplant CSF-1 therapy expands recipient macrophages and ameliorates GVHD after allogeneic hematopoietic cell transplantation [PDF]

, 2011
Host macrophages protect against graft-versus-host disease in part by engulfing donor T cells and inhibiting their ...
Abe, Allavena, Alyea, Andrew Chow, Banovic, Bartocci, Beilhack, Bishop, Blazar, Blazar, Blazar, Bogunovic, Burnett, Cecchini, Chen Liu, Chitu, Collin, Cooke, Dai, Daigo Hashimoto, Dreger, Drobyski, Duffner, E. Richard Stanley, Ehlenberger, Facon, Felix, Florent Ginhoux, Fraser, Garcia, Ginhoux, Ginhoux, Ginhoux, Haniffa, Helft, Hill, Hill, Hume, Ide, Jasperson, Jenq, Jordi C. Ochando, Koyama, Krenger, Krenger, Lin, MacDonald, Maris, Marylene Leboeuf, Matozaki, Melanie Greter, Mempel, Menke, Merad, Merad, Mielcarek, Miller, Miriam Merad, Na, Namba, Nemunaitis, Nico van Rooijen, Okamoto, Panoskaltsis-Mortari, Paul S. Frenette, Pavletic, Peggs, Peter S. Heeger, Pollard, Rabinowe, Rozemuller, Shlomchik, Sorror, Sudo, Tacke, Takai, Takanori Teshima, Takenaka, Teshima, van Besien, Van Rooijen, Wiktor-Jedrzejczak, Wing-Hong Kwan, Wynn, Yoshida, Yuya Kunisaki, Yvonne Saenger, Zhang, Zhang   +88 more
core   +4 more sources

CLDN18.2 CAR‐derived Extracellular Vesicle Immunotherapy Improves Outcome in Murine Pancreatic Cancer

Advanced Healthcare Materials, EarlyView.
CLDN18.2 CAR‐T cell‐derived small extracellular vesicles (CAR‐sEVs) display potent cytotoxicity and prolong survival in preclinical pancreatic cancer models. They contain functional CAR proteins and granzyme B, exhibit antigen specificity, and effectively target tumor cells while sparing healthy cells.
Yue Qing, Ke Jiang, Hua Jiang, Yaru Zhao, Chu‐Hu Lai, Alexandra Aicher, Zonghai Li, Christopher Heeschen   +7 more
wiley   +1 more source

Skin-Limited Graft-versus-Host Disease after Pancreatic Transplantation

Case Reports in Transplantation, 2017
Introduction. The phenomenon of graft-versus-host disease, a solid organ transplant recipient, is a rare development with a very poor prognosis. Case Presentation.
Muneeb Ilyas, Elika Hoss, David J. DiCaudo, Hasan Khamash, Mark R. Pittelkow, Amit Sharma   +5 more
doaj   +1 more source

Non-myeloablative allogeneic peripheral stem cell transplantation for multiple myeloma [PDF]

, 2004
Objective. To present an institution's 2-year experience of non-myeloablative allogeneic stem cell transplantation among Chinese patients. Design. Retrospective study. Setting.
Au, WY, Chim, CS, Kwong, YL, Liang, R, Lie, AKW, Ma, SY   +5 more
core  

β‐1,3 Glucan Microparticles & Nanoparticles: Fabrication Methods & Applications in Immunomodulation & Targeted Drug Delivery

Advanced Healthcare Materials, EarlyView.
Beta‐glucans have gained significant attention as an immunomodulatory biomaterial with cell‐targeting capabilities. This review comprehensively outlines the design and fabrication methods for producing beta‐glucan particles at both the micro and nanoscale and their applications in immune cell targeting, immunomodulation, and drug delivery ...
Nate Dowdall, Todd Hoare
wiley   +1 more source

Non-infectious pulmonary complications of hematopoietic stem cell transplantation [PDF]

, 2014
Noninfectious pulmonary complications of hematopoietic stem cell transplant are currently more prevalent than infectious complications. Unfortunately, the pathophysiology basis is not completely understood.
Baloglu, Orkun, McArthur, Jennifer, Rowan, Courtney   +2 more
core   +1 more source