Results 71 to 80 of about 179,002 (365)

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

Interleukin-10 spot-forming cells as a novel biomarker of chronic graft-versus-host disease

Haematologica, 2013
Although there are National Institutes of Health consensus criteria for the global assessment of chronic graft-versus-host disease, no validated biomarkers have been established for this disease.
Masahiro Hirayama, Eiichi Azuma, Atsuko Nakagawa-Nakazawa, Tadashi Kumamoto, Shotaro Iwamoto, Keishiro Amano, Shigehisa Tamaki, Eiji Usui, Yoshihiro Komada   +8 more
doaj   +1 more source

Phase diagram of epidemic spreading - unimodal vs. bimodal probability distributions [PDF]

, 2009
The disease spreading on complex networks is studied in SIR model. Simulations on empirical complex networks reveal two specific regimes of disease spreading: local containment and epidemic outbreak. The variables measuring the extent of disease spreading are in general characterized by a bimodal probability distribution.
arxiv   +1 more source

Heparanase Promotes Engraftment and Prevents Graft versus Host Disease in Stem Cell Transplantation [PDF]

, 2010
Heparanase, endoglycosidase that cleaves heparan sulfate side chains of heparan sulfate proteoglycans, plays important roles in cancer metastasis, angiogenesis and inflammation.Applying a mouse model of bone marrow transplantation and transgenic mice ...
Arnon Nagler, Derya Unutmaz, Eyal Zcharia, Israel Vlodavsky, Lola Weiss, Menachem Bitan, Michael Zeira, Shimon Slavin   +7 more
core   +3 more sources

Immunosuppressive Drugs in Early Systemic Sclerosis and Prevention of Damage Accrual

Arthritis Care &Research, Volume 77, Issue 5, Page 640-648, May 2025.
Objective Organ damage in patients with systemic sclerosis (SSc) in individual organs such as the lungs may be prevented by receiving immunosuppressive drugs (ISs). A new measure of global organ damage, the Scleroderma Clinical Trials Consortium Damage Index (SCTC‐DI), has allowed us to investigate whether receiving ISs may reduce global organ damage ...
Murray Baron, Mandana Nikpour, Dylan Hansen, Susanna Proudman, Wendy Stevens, on behalf of the Australian Scleroderma Interest Group and the Canadian Scleroderma Research Group, Joanne Sahhar, Nava Ferdowsi, Kathleen Morrisroe, Laura Ross, Gene Siew Ngian, Jennifer Walker, Janet Roddy, Lauren Host, Mohammed Osman, Peter Docherty, Paul Fortin, Marvin Jacob Fritzler, Genevieve Gyger, Alena Ikic, Niall Jones, Elzbieta Kaminska, Maggie Larche, Sophie Ligier, Ada Man, Ariel Masetto, Janet Pope, David Robinson, Tatiana Sofia Rodriguez‐Reyna, Mianbo Wang   +29 more
wiley   +1 more source

Membranous nephropathy and lupus-like syndrome after hematopoietic cell transplantation: a case report [PDF]

, 2010
Introduction The kidney is increasingly recognised as a target organ of chronic graft-versus-host disease after hematopoietic cell transplantation in the context of the development of the nephrotic syndrome.
A Chang, A Tyndall, Constantina Petraki, Dimitris Xydakis, Eleftheria Vardaki, Eugene Daphnis, GS Chan, Ioannis Petrakis, Irene Xylouri, J Lin, JH Lee, K Brukamp, Kostas Perakis, Kostas Stylianou, M Higman, Michael Alexandrakis, ML Troxell, P Reddy, Peggy Kanellou, PS Rao, R Srinivasan, Spyros Stratigis, Stavros Stratakis, Theodora Katsarou, Vasiliki Mavroeidi   +24 more
core   +3 more sources

3D Bioprinting of Thick Adipose Tissues with Integrated Vascular Hierarchies

Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
An advanced 3D bioprinting technique is used here to create thick adipose tissues with a central, vessel and extensive branching. The construct is made using alginate, gelatin and collagen‐based bioinks. Flow through the complex vessel network is demonstrated as well as its successful integration with a femoral artery following implantation in a rat ...
Idit Goldfracht, Majd Machour, Inbal Michael, Maria Bulatova, Janette Zavin, Shulamit Levenberg   +5 more
wiley   +1 more source

Stable Radical Polymers as New Electroactive Materials: Synthesis, Properties, and Emerging Applications

Advanced Functional Materials, EarlyView.
This review covers the recent advances in the synthesis and properties of stable radical polymers (SRPs) and presents their applications in electronics, magnetics, optoelectronics, and biomedicines. The review concludes with a discussion of the challenges in radical chemistry and functionalization, while shedding light on the groundbreaking potential ...
Yufeng Xiong, Yingjiang Li, Xinfang Cui, Shiwei Li, Xiangdong Peng, Yanyun Ju, Tong Zhou, Rui Feng, Yang Zhang, Zehong Wang, Qing Wang, Lijie Dong   +11 more
wiley   +1 more source

Graft Versus Host Disease [PDF]

, 2018
The esophagus may be affected during the course of bone marrow transplantation. In addition both chemotherapy and radiotherapy may lead to esophageal injury, including graft versus host disease.
Takahisa Yamasaki, Ronnie Fass, Nina Bandyopadhyay, Colin Hemond   +3 more
openaire   +2 more sources

Biologically‐Inspired Melt Electrowriting for the Generation of Highly Biomimetic Functional Myocardium

Advanced Functional Materials, EarlyView.
In this work, melt electrowriting is used to fabricate a 3D printed scaffold design that generates engineered cardiac tissues with in‐plane contraction, mimicking natural myocardium. It is shown that these tissues display advanced maturation and functionality.
Olalla Iglesias‐García, María Flandes‐Iparraguirre, Pilar Montero‐Calle, Ricardo M. Rosales, Asier Ullate‐Agote, Andrea Sánchez‐Bueno, Eduardo Larequi, Ilazki Anaut‐Lusar, Nicolás Laita, Aida Oliván‐Viguera, Elena Iglesias, Gloria Abizanda, Patxi San Martín‐Úriz, Paula Aguirre‐Ruiz, Xabier L. Aranguren, Manuel García de Yébenes, Juan José Gavira, Miguel Ángel Martínez, Estefanía Peña, Manuel Doblaré, Elena M. de‐Juan‐Pardo, Esther Pueyo, Felipe Prosper, Manuel M. Mazo Vega   +23 more
wiley   +1 more source