Results 121 to 130 of about 5,921,684 (304)

Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling

FEBS Open Bio, EarlyView.
Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt, Annika Winbo, Jenny Malmström   +2 more
wiley   +1 more source

Preliminary report on impact of pretransplant dialysis on early graft function: peritoneal versus hemodialysis.

, 2004
Delayed graft function and acute renal failure after kidney transplant negatively influence graft outcome. It has been reported that pretransplantation peritoneal dialysis (PD) instead of hemodialysis (HD) correlated with better short-term graft outcome ...
BEATINI M, GHINOLFI D, PERFUMO F, VALENTE, UMBERTO, SALTALAMACCHIA L, FONTANA I, BASILE G, SANTORI, GREGORIO, BERTOCCHI M, BONIFAZIO L, GINEVRI F   +10 more
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Clinical Impacts of Allograft Biopsy in Renal Transplant Recipients 10 Years or Longer After Transplantation

Transplant International
We aimed to investigate the clinical value of allograft biopsy performed long after renal transplantation. We retrospectively evaluated 99 allograft biopsies in recipients with transplantation vintages of 10 years or longer.
Tomoko Namba-Hamano, Takayuki Hamano, Takayuki Hamano, Yohei Doi, Atsuko Hiraoka, Hiroaki Yonishi, Shinsuke Sakai, Atsushi Takahashi, Masayuki Mizui, Shigeaki Nakazawa, Kazuaki Yamanaka, Yoichi Kakuta, Ryoichi Imamura, Norio Nonomura, Yoshitaka Isaka   +14 more
doaj   +1 more source

A Low Psoas Muscle Index Was Associated With a Poorer Overall Survival in Patients Who Underwent Percutaneous Nephrostomy

Aging and Cancer, EarlyView.
In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara, Takashi Kawahara, Kazuhide Makiyama, Hiroji Uemura   +3 more
wiley   +1 more source

Estimated and measured donor creatinine clearance are poor predictors of long-term renal graft function and survival

, 2002
The objective of this study was to evaluate estimated and measured donor renal function in predicting graft function long-term and to identify donor criteria associated with nonacceptable graft prognosis.
Schuck, O, Vitko, S, Pokorna, E, Ekberg, Henrik   +3 more
core   +1 more source

Delayed graft function in renal transplantation : aetiology and impact on graft outcome

, 2001
Bibliography: leaves 61-75.The optimal therapy for most patients with end stage renal disease is renal transplantation. This form of therapy results in improved quality of life, decreased medical expense, and perhaps a survival advantage for the ...
Douie, Walter James Percival
core   +1 more source

Benefit of Islet Transplantation in Type 1 Diabetes: A Systematic Review and Meta-Analysis

Journal of Clinical Question
Introduction: Type 1 diabetes (T1D) continues to impose substantial global health burdens, including recurrent severe hypoglycemia and risks of long-term complications.
Xiao-Qin Wu, Jin He, Zhen-Guang Wang, Hong Qin, Jing-Zhu Cao   +4 more
doaj   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

SGLT2 inhibitors in kidney transplant recipients: metabolic changes, potassium-related safety and implications for albuminuria assessment

Frontiers in Transplantation
BackgroundSodium-glucose cotransporter-2 inhibitors (SGLT2i) are established therapies in chronic kidney disease (CKD), but comparative data in kidney transplant recipients (KTR) remain limited.MethodsWe retrospectively matched 100 KTR receiving SGLT2i ...
Lino Henkel, Lisa Ingmanns, Florian Westphal, Amélie F. Menke, Hermann Pavenstädt, Ulrich Jehn, Göran R. Boeckel, Stefan Reuter   +7 more
doaj   +1 more source