Results 101 to 110 of about 5,921,684 (304)
Brazilian Journal of Medical and Biological Research, 2006 We conducted a retrospective analysis of the influence of full doses of calcineurin inhibitors [8-10 mg kg-1 day-1 cyclosporine (N = 80), or 0.2-0.3 mg kg-1 day-1 tacrolimus (N = 68)] administered from day 1 after transplantation on the transplant ...
L.A. Silva +8 more
doaj +1 more source
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Targeted delivery for treatments for restenosis and vein graft disease [PDF]
, 2012 Surgery to restore blood flow in arteries blocked by atherosclerotic plaque is a common treatment in cardiovascular disease. Longtermcomplications of surgical treatment are vein graft disease and restenosis, a renarrowing of the blood vessel after ...
Thomas, Anita C
core +1 more source
Risk factors for delayed renal graft function and their impact on renal transplantation outcome
, 2007 OBJECTIVE: The objective of this study was to evaluate the risk factors for delayed graft function (DGF) and their influence on renal graft outcome. PATIENTS AND METHODS: We reviewed 1462 consecutive renal transplantation and identified 245 patients (17 ...
Moreira, P +6 more
core +1 more source
Трансплантология (Москва), 2018 Introduction: The expansion of the criteria for donor organ retrieval contributes to an increase in the number of kidney transplantations to elderly recipients; but in view of reduced requirements to donor organ quality, a further analysis of ...
N. V. Shmarina +3 more
doaj +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Primary liver graft dysfunction and non-function: integrative literature review.
, 2019 Avoiding deaths in the waiting list for an organ is no longer the only focus of the transplant teams attention. Research and care in clinical practice has been increasingly focused on post transplant graft survival and functioning.
Hérica Pinheiro Correa (6626393) +4 more
core +1 more source
, 2005 Metabolic demand and renal mass supply affecting the early graft function after living donor kidney transplantation.BackgroundGraft mass has been demonstrated to be a determinant of outcome after kidney transplantation. An insufficient nephron might fail
김순일 +9 more
core +2 more sources
The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection
Molecular Oncology, EarlyView.Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński +12 more
wiley +1 more source
L-Strut Cartilage Graft: A Versatile Graft in Functional Rhinoplasty
Indian Journal of Otolaryngology and Head & Neck SurgeryAnterior and high septal deviation can severely affect the functional and cosmetic outcomes of a patient. Conventional septoplasty would not be sufficient in these conditions to restore the functionality and aesthetics of a nose, and the majority of the patients require L-shaped grafts for the reconstruction of the septum.
Pradeep Pradhan, Mebarimon Kharwanlang
openaire +3 more sources