Results 81 to 90 of about 5,921,684 (304)

Pretransplant pulmonary hypertension and long-term allograft right ventricular function [PDF]

, 2009
Graft right ventricular (RV) function is compromised directly posttransplant, especially in heart transplantation (HTx) recipients with pretransplant pulmonary hypertension (PH).
Wigger, Eric, Stoupis, Christoforos, Carrel, Thierry, Feller, Martin, Hullin, Roger, Tanner, Hildegard, Mohacsi, Paul, Wahl, Andreas, Mohacsi P, Feller M, Carrel T, Wahl A, Tanner H, Wigger E, Stoupis C, Hullin R   +15 more
core   +2 more sources

Association of Intraoperative Hemodynamic Parameters and Creatinine Levels with Early Graft Function Following Living Donor Kidney Transplantation: A Retrospective Study

Bali Journal of Anesthesiology
Background: Intraoperative hemodynamic management is critical for optimizing graft function in kidney transplantation. The study aimed to investigate the association between intraoperative mean arterial pressure (MAP) and central venous pressure (CVP ...
Juni Kurniawaty, Novita Intan Arovah
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Ferroptosis Inhibition Enhances Liver and Lung Graft Function

Dataset for the article titled "Ferroptosis Inhibition Enhances Liver and Lung Graft Function
Scarpellini, Camilla
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Cognitive Function in Candidates for Coronary Artery Bypass Graft Surgery

, 2006
Cognitive Function in Candidates for Coronary Artery Bypass Graft ...
MUC Worcester (14449266), CS Ernest (15836381), Michael Le Grande (13085268), J Tatoulis (13417257), BM Murphy (14112315), AJ Goble (15836342), RO Higgins (14447523), PC Elliott (15836345), N Genardini (13417287)   +8 more
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

DE NOVO ANTI HLA ANTIBODIES AFTER KIDNEY TRANSPLANTATION: CLINICAL SIGNIFICANCE AND ASSOCIATION WITH GRAFT FUNCTION [PDF]

Archives of the Balkan Medical Union, 2017
Background. Kidney transplantation (TR) is the best treatment of chronic kidney disease. Chronic cellular and antibody mediated rejections have still major impact on graft survival.
Galina Severova, Igor Nikolov, Koco Cakalaroski, Aleksandar Sikole, Lada Trajceska, Goce Spasovski, Kocho Dimitrovski, Irena Rambabova Busljetic, Ninoslav Ivanovski   +8 more
doaj  

Haploidentical Hematopoietic Cell Transplantation for Infants With X‐Linked Severe Combined Immunodeficiency Using Post‐Transplant Cyclophosphamide

Pediatric Blood &Cancer, EarlyView.
Shuhei Takahashi, Akito Kawachi, Dan Tomomasa, Eri Watanabe, Yuji Fujita, Yuya Sato, Masahiro Sekiguchi, Kentaro Watanabe, Moe Hidaka, Akihiro Hoshino, Takahiro Kamiya, Masatoshi Takagi, Hirokazu Kanegane, Motohiro Kato   +13 more
wiley   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source