Results 91 to 100 of about 5,921,684 (304)

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Can transplant renal scintigraphy predict the duration of delayed graft function? A dual center retrospective study - Fig 3 [PDF]

, 2018
Kaplan-Meier curves, showing the incidence of delayed graft function within the first month after kidney transplantation (censored for patients with DGF > 30 days, n = 10) for (A) qualitative grading, (B) TFS, (C) cTER, (D) MUC10, and (E) Average upslope.
Berger, Stefan P, Stefan P. Berger, de Vries, Aiko P J, Pol, Robert A; id_orcid, Glaudemans, A.W.J.M., Robert A. Pol, Slart, Riemer H J A, Aiko P. J. de Vries, Berger, S.P., Aiko P. J. de Vries (404823), Berger, Stefan P., Stan Benjamens, Robert A Pol, Andor W. J. M. Glaudemans (4989905), Geus-Oei, L.F. de, Stan Benjamens (4989908), Stefan P. Berger (4989899), Pol, Robert A., Lioe-Fee de Geus-Oei, Aiko P J de Vries, Benjamens, Stan; id_orcid, Andor W J M Glaudemans, Benjamens, S., Lioe-Fee de Geus-Oei (715744), Benjamens, Stan, Riemer H J A Slart, Glaudemans, Andor W J M, Glaudemans, Andor W.J.M., Glaudemans, Andor W J M; id_orcid, de Geus-Oei, Lioe-Fee, Stefan P Berger, Pol, R.A., de Vries, Aiko P.J., Riemer H. J. A. Slart, Pol, Robert A, Robert A. Pol (4989902), Riemer H. J. A. Slart (3622058), Vries, A.P.J. de, Slart, Riemer H.J.A., Slart, R.H.J.A., Andor W. J. M. Glaudemans   +40 more
core   +2 more sources

Association between Early Resistive Index Measurement and Early Graft Function and Long-Term Graft Survival after Kidney Transplantation: an Evidence-based Clinical Review

Acta Medica Indonesiana, 2019
Background: resistive index (RI) is highly utilised to assess the graft function using Doppler ultrasonography. The RI has been shown as the best ultrasound parameter to assess kidney allograft dysfunction.
Pande Made Wisnu Tirtayasa, Gede Wirya Kusuma Duarsa, Gerhard Reinaldi Situmorang, I Wayan Yudiana, Kadek Budi Santosa, Anak Agung Gde Oka, Arry Rodjani, Nur Rasyid   +7 more
doaj   +2 more sources

Association between peri-transplant acid-base parameters and graft dysfunction types in kidney transplantation

Romanian Journal of Internal Medicine
Perioperative acid-base disturbance could be informative regarding the possible slow graft function (SGF) or delayed graft function (DGF) development. There is a lack of data regarding the relationship between perioperative acid-base parameters and graft
Căluşi Teodor, Sorohan Bogdan, Iordache Alexandru, Domnişor Liliana, Purcaru Florea   +4 more
doaj   +1 more source

Changes in rat intestinal motility and absorption following intestinal transplantation: an experimental study

Transplant International
Intestinal transplantation (ITx) is a life-saving procedure for patients with complicated intestinal failure. In the acute phase, allograft permeability increases primarily due to ischemia-reperfusion injury. However, long-term allograft physiology after
Antoine Dubois, Antoine Dubois, Antoine Dubois, Amélie Leenders, Gert De Hertogh, Alice Rustichelli, Caroline Boelhouwer, Caroline Boelhouwer, Tine Wylin, Veerle Heedfeld, Eliano Bonaccorsi-Riani, Jacques Pirenne, Jacques Pirenne, Tim Vanuytsel, Tim Vanuytsel, Ricard Farré, Laurens J. Ceulemans, Laurens J. Ceulemans   +17 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Comparative Analysis of Islet Auto-Transplantation Outcome Classification Systems: Evaluating Concordance, Feasibility, and a Data-Driven Approach

Transplant International
A standardized approach to assessing islet autotransplantation outcomes is crucial for evaluating graft function and guiding clinical decisions. This study compares the performance of existing classification systems—Milan, Minneapolis, Chicago, Leicester,
Davide Catarinella, Paola Magistretti, Raffaella Melzi, Alessia Mercalli, Stefano Tentori, Chiara Gremizzi, Vera Paloschi, Simona Sala, Libera Valla, Francesca Aleotti, Sabrina Costa, Francesco De Cobelli, Francesco De Cobelli, Rossana Caldara, Lorenzo Piemonti, Lorenzo Piemonti   +15 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

How Much Does Graft Function Cost Us? A Financial Analysis of Delayed Graft Function in Kidney Transplant Recipients

, 2019
Purpose: Kidney transplant recipients (KTR) who receive dialysis post-transplant experience worse outcomes during the first year post-transplant. Whether KTR discharged with elevated levels of serum creatinine but not receiving dialysis experience ...
Abouljoud, Marwan, Crombez, Catherine, Bajjoka, I, Yaldo, A   +3 more
core   +1 more source